Compile Data Set for Download or QSAR
Found 159 with Last Name = 'shin' and Initial = 'ya'
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))TBA
LigandPNGBDBM50550263(CHEMBL4748750)copy SMILES
Affinity DataIC50: 1.60nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060496(CHEMBL3394399)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060501(CHEMBL3394394)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060491(CHEMBL3394404)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060495(CHEMBL3394400)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060409(CHEMBL3394415)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550252(CHEMBL4779054)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550263(CHEMBL4748750)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human 11beta-HSD1 expressed in microsomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060410(CHEMBL3394414)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550247(CHEMBL4747534)copy SMILES
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060492(CHEMBL3394403)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060493(CHEMBL3394402)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550255(CHEMBL4746745)copy SMILES
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060411(CHEMBL3394413)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060498(CHEMBL3394397)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550251(CHEMBL4750382)copy SMILES
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060412(CHEMBL3394412)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060494(CHEMBL3394401)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060488(CHEMBL3394407)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550254(CHEMBL4779594)copy SMILES
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))TBA
LigandPNGBDBM50060409(CHEMBL3394415)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550263(CHEMBL4748750)copy SMILES
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060499(CHEMBL3394396)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550268(CHEMBL4746670)copy SMILES
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
TIUMBIO CO., LTD.

US Patent
LigandPNGBDBM311398(US10155763, Example 6)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMAssay Description:The kinase activity of ALK5 was assessed by measuring radiolabelled phosphate[33P] incorporation into the generic substrate, casein. The kinase domai...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C70HKUS Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060500(CHEMBL3394395)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060490(CHEMBL3394405)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
TIUMBIO CO., LTD.

US Patent
LigandPNGBDBM311395(US10155763, Example 2)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:The kinase activity of ALK5 was assessed by measuring radiolabelled phosphate[33P] incorporation into the generic substrate, casein. The kinase domai...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C70HKUS Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060409(CHEMBL3394415)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human 11beta-HSD1 transfected in HEK293 cells assessed as conversion of cortisone to cortisol after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060415(CHEMBL3394409)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060413(CHEMBL3394411)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550266(CHEMBL4785894)copy SMILES
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550264(CHEMBL4747303)copy SMILES
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550265(CHEMBL4759459)copy SMILES
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550249(CHEMBL4742750)copy SMILES
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550260(CHEMBL4788862)copy SMILES
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060487(CHEMBL3394408)copy SMILEScopy InChI
Affinity DataIC50: 8.70nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550262(CHEMBL4762396)copy SMILES
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550250(CHEMBL4780484)copy SMILES
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550261(CHEMBL4779099)copy SMILES
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060414(CHEMBL3394410)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550259(CHEMBL4759090)copy SMILES
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550253(CHEMBL4743768)copy SMILES
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
TIUMBIO CO., LTD.

US Patent
LigandPNGBDBM311399(US10155763, Example 7)copy SMILEScopy InChI
Affinity DataIC50: 10.3nMAssay Description:The kinase activity of ALK5 was assessed by measuring radiolabelled phosphate[33P] incorporation into the generic substrate, casein. The kinase domai...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C70HKUS Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
TIUMBIO CO., LTD.

US Patent
LigandPNGBDBM311400(US10155763, Example 9)copy SMILEScopy InChI
Affinity DataIC50: 11.5nMAssay Description:The kinase activity of ALK5 was assessed by measuring radiolabelled phosphate[33P] incorporation into the generic substrate, casein. The kinase domai...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C70HKUS Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550267(CHEMBL4756835)copy SMILES
Affinity DataIC50: 12nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
TIUMBIO CO., LTD.

US Patent
LigandPNGBDBM311397(US10155763, Example 4)copy SMILEScopy InChI
Affinity DataIC50: 12.1nMAssay Description:The kinase activity of ALK5 was assessed by measuring radiolabelled phosphate[33P] incorporation into the generic substrate, casein. The kinase domai...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C70HKUS Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060497(CHEMBL3394398)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50550258(CHEMBL4756971)copy SMILES
Affinity DataIC50: 18nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P930BPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Republic of Korea; Research Institute of Pharmaceutical Science and College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060489(CHEMBL3394406)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of 11beta-HSD1 in HEK293 cell microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B32ZTPubMed
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