Compile Data Set for Download or QSAR
Found 162 with Last Name = 'chou' and Initial = 'yc'
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380413(CHEMBL2018573)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380418(CHEMBL2018571)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380417(CHEMBL2018485)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380410(CHEMBL2018484)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380417(CHEMBL2018485)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced tango beta-arrestin recruitment preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380414(CHEMBL2018467)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380437(CHEMBL2018474)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380413(CHEMBL2018573)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced tango beta-arrestin recruitment preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380418(CHEMBL2018571)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced tango beta-arrestin recruitment preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380411(CHEMBL2018465)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380425(CHEMBL2018460)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380410(CHEMBL2018484)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced tango beta-arrestin recruitment preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380412(CHEMBL2018486)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380443(CHEMBL2018480)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380415(CHEMBL2018481)copy SMILEScopy InChI
Affinity DataIC50: 84.7nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380409(CHEMBL2016597)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179235(2-{5-[4-(7-propyl-3-trifluoromethylbenzo[d]isoxazo...)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DS5PubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179229(2-{5-[3-(3-phenyl-7-propylbenzo[d]isoxazol-6-yloxy...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DS5PubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179225(2-{4-[3-(3-phenyl-7-propylbenzo[d]isoxazol-6-yloxy...)copy SMILEScopy InChI
Affinity DataIC50: 127nMAssay Description:Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DS5PubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179236(2-(5-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)copy SMILEScopy InChI
Affinity DataIC50: 152nMAssay Description:Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380432(CHEMBL2018469)copy SMILEScopy InChI
Affinity DataIC50: 152nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380416(CHEMBL2018482)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380440(CHEMBL2018477)copy SMILEScopy InChI
Affinity DataIC50: 181nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380429(CHEMBL2018464)copy SMILEScopy InChI
Affinity DataIC50: 211nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380416(CHEMBL2018482)copy SMILEScopy InChI
Affinity DataIC50: 213nMAssay Description:Inhibition of human CYP2C9 using tolbutamide as substrate by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380411(CHEMBL2018465)copy SMILEScopy InChI
Affinity DataIC50: 221nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced tango beta-arrestin recruitment preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380426(CHEMBL2018461)copy SMILEScopy InChI
Affinity DataIC50: 228nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380442(CHEMBL2018479)copy SMILEScopy InChI
Affinity DataIC50: 239nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380414(CHEMBL2018467)copy SMILEScopy InChI
Affinity DataIC50: 284nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced tango beta-arrestin recruitment preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380422(CHEMBL2018457)copy SMILEScopy InChI
Affinity DataIC50: 286nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380423(CHEMBL2018458)copy SMILEScopy InChI
Affinity DataIC50: 297nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380416(CHEMBL2018482)copy SMILEScopy InChI
Affinity DataIC50: 301nMAssay Description:Inhibition of human CYP3A4 using testosterone as substrate by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380439(CHEMBL2018476)copy SMILEScopy InChI
Affinity DataIC50: 326nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380410(CHEMBL2018484)copy SMILEScopy InChI
Affinity DataIC50: 392nMAssay Description:Inhibition of human CYP2D6 using bufuralol as substrate by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179227(2-(5-(2-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)copy SMILEScopy InChI
Affinity DataIC50: 422nMAssay Description:Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DS5PubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380444(CHEMBL2018483)copy SMILEScopy InChI
Affinity DataIC50: 492nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380428(CHEMBL2018463)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380420(CHEMBL2018456)copy SMILEScopy InChI
Affinity DataIC50: 548nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179240(3-{5-[3-(7-propyl-3-trifluoromethylbenzo[d]isoxazo...)copy SMILEScopy InChI
Affinity DataIC50: 584nMAssay Description:Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DS5PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380416(CHEMBL2018482)copy SMILEScopy InChI
Affinity DataIC50: 663nMAssay Description:Inhibition of human CYP2D6 using bufuralol as substrate by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380431(CHEMBL2018468)copy SMILEScopy InChI
Affinity DataIC50: 702nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380419(CHEMBL2018454)copy SMILEScopy InChI
Affinity DataIC50: 718nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380435(CHEMBL2018472)copy SMILEScopy InChI
Affinity DataIC50: 743nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380438(CHEMBL2018475)copy SMILEScopy InChI
Affinity DataIC50: 752nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179226(2-{5-[3-(3-cyano-7-propyl-1H-indol-6-yloxy)propoxy...)copy SMILEScopy InChI
Affinity DataIC50: 759nMAssay Description:Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DS5PubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179233(2-{4-[4-(7-propyl-3-trifluoromethylbenzo[d]isoxazo...)copy SMILEScopy InChI
Affinity DataIC50: 774nMAssay Description:Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DS5PubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380445(CHEMBL2018572)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50380424(CHEMBL2018459)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at S1P1 receptor expressed in HEK293 cells assessed as inhibition of S1P-induced cAMP response after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z1HPubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179234(2-{6-[3-(7-propyl-3-trifluoromethylbenzo[d]isoxazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+3nMAssay Description:Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78DS5PubMed
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