Compile Data Set for Download or QSAR
Found 100 with Last Name = 'han' and Initial = 'yf'
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Weizmann Institute of Science

LigandPNGBDBM10439((5S)-5-[(10-{[(5S)-2-oxo-1,2,5,6,7,8-hexahydroquin...)copy SMILEScopy InChI
Affinity DataKi:  0.800nM ΔG°:  -51.4kJ/mole IC50: 2.40nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50387918(CHEMBL2058680 | US9283222, 459)copy SMILEScopy InChI
In DepthDetails
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Weizmann Institute of Science

LigandPNGBDBM10440((5S)-5-[(12-{[(5S)-2-oxo-1,2,5,6,7,8-hexahydroquin...)copy SMILEScopy InChI
Affinity DataKi:  4.5nM ΔG°:  -47.2kJ/mole IC50: 16nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10440((5S)-5-[(12-{[(5S)-2-oxo-1,2,5,6,7,8-hexahydroquin...)copy SMILEScopy InChI
Affinity DataKi:  19.6nM ΔG°:  -43.6kJ/mole IC50: 52nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5R69PubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10441((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...)copy SMILEScopy InChI
Affinity DataKi:  47.1nM ΔG°:  -41.4kJ/mole IC50: 114nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5R69PubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Weizmann Institute of Science

LigandPNGBDBM10441((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...)copy SMILEScopy InChI
Affinity DataKi:  175nM ΔG°:  -38.2kJ/mole IC50: 414nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM9047(Bis-THA inhibitor 5 | CHEMBL73800 | Hexylene-Linke...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM8962(Bis-THA inhibitor 4 | CHEMBL179732 | N-[5-(1,2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10469(Bis-THA inhibitor 1c | Bis-THA inhibitor 8 | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 31nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10470(Bis-THA inhibitor 1d | Bis-THA inhibitor 9 | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10446(2-methyl-N-{9-[(2-methylquinolin-4-yl)amino]nonyl}...)copy SMILEScopy InChI
Affinity DataIC50: 54.1nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10452(Bivalent 4-Aminoquinoline 9f | N,N-di-4-Quinolyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 87.8nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 92nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10453(Bivalent 4-Aminoquinoline 9g | N-[8-(quinolin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 94.3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM10478(A2A.2HCl | Bis-THA inhibitor 1 | CHEMBL213377 | N-...)copy SMILEScopy InChI
Affinity DataIC50: 102nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM9047(Bis-THA inhibitor 5 | CHEMBL73800 | Hexylene-Linke...)copy SMILEScopy InChI
Affinity DataIC50: 119nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10454(Bivalent 4-Aminoquinoline 9h | N-[9-(quinolin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 124nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10447(2-methyl-N-{10-[(2-methylquinolin-4-yl)amino]decyl...)copy SMILEScopy InChI
Affinity DataIC50: 143nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10444(2-methyl-N-{7-[(2-methylquinolin-4-yl)amino]heptyl...)copy SMILEScopy InChI
Affinity DataIC50: 148nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10439((5S)-5-[(10-{[(5S)-2-oxo-1,2,5,6,7,8-hexahydroquin...)copy SMILEScopy InChI
Affinity DataIC50: 151nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5R69PubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM10479(A3A.2HCl | Bis-THA inhibitor 2 | CHEMBL378006 | N-...)copy SMILEScopy InChI
Affinity DataIC50: 152nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10463(Bivalent 4-Aminopyridine 12i | N,N-di-4-Pyridyl-1,...)copy SMILEScopy InChI
Affinity DataIC50: 152nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM10469(Bis-THA inhibitor 1c | Bis-THA inhibitor 8 | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 155nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10480(A4A.2HCl | Bis-THA inhibitor 3 | CHEMBL211313 | N-...)copy SMILEScopy InChI
Affinity DataIC50: 157nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10445(2-methyl-N-{8-[(2-methylquinolin-4-yl)amino]octyl}...)copy SMILEScopy InChI
Affinity DataIC50: 161nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM10470(Bis-THA inhibitor 1d | Bis-THA inhibitor 9 | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 167nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10451(Bivalent 4-Aminoquinoline 9e | N-[6-(quinolin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 215nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 223nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10464(Bivalent 4-Aminopyridine 12j | bis((2R,3R)-2,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 244nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM10480(A4A.2HCl | Bis-THA inhibitor 3 | CHEMBL211313 | N-...)copy SMILEScopy InChI
Affinity DataIC50: 252nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10479(A3A.2HCl | Bis-THA inhibitor 2 | CHEMBL378006 | N-...)copy SMILEScopy InChI
Affinity DataIC50: 254nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10448(2-methyl-N-{11-[(2-methylquinolin-4-yl)amino]undec...)copy SMILEScopy InChI
Affinity DataIC50: 312nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM8962(Bis-THA inhibitor 4 | CHEMBL179732 | N-[5-(1,2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 329nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM10442(9-N-heptyl-amino-1,2,3,4-tetrahydroacridine hydroc...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10462(Bivalent 4-Aminopyridine 12h | bis((2R,3R)-2,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 364nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10465(Bivalent 4-Aminopyridine 12k | bis((2R,3R)-2,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 403nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10442(9-N-heptyl-amino-1,2,3,4-tetrahydroacridine hydroc...)copy SMILEScopy InChI
Affinity DataIC50: 454nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10455(Bivalent 4-Aminoquinoline 9i | N-[10-(quinolin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 483nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetG-protein coupled receptor 52(Homo sapiens (Human))TBA
LigandPNGBDBM50556717(CHEMBL4780703)copy SMILES
Affinity DataIC50: 630nMAssay Description:Antagonist activity at GPR52 (unknown origin) expressed in HEK293 cells assessed as inhibition of WO459-induced cAMP accumulation preincubated for 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P9327PubMed
TargetG-protein coupled receptor 52(Homo sapiens (Human))TBA
LigandPNGBDBM50556698(CHEMBL2375494)copy SMILES
Affinity DataIC50: 650nMAssay Description:Antagonist activity at GPR52 (unknown origin) expressed in HEK293 cells assessed as inhibition of WO459-induced cAMP accumulation preincubated for 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P9327PubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10478(A2A.2HCl | Bis-THA inhibitor 1 | CHEMBL213377 | N-...)copy SMILEScopy InChI
Affinity DataIC50: 711nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R9QPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10456(Bivalent 4-Aminoquinoline 9k | N-[12-(quinolin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 786nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10460(Bivalent 4-Aminopyridine 12f | bis((2R,3R)-2,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 809nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetG-protein coupled receptor 52(Homo sapiens (Human))TBA
LigandPNGBDBM50556715(CHEMBL4782344)copy SMILES
Affinity DataIC50: 880nMAssay Description:Antagonist activity at GPR52 (unknown origin) expressed in HEK293 cells assessed as inhibition of WO459-induced cAMP accumulation preincubated for 15...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P9327PubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute of Science

LigandPNGBDBM10461(Bivalent 4-Aminopyridine 12g | bis((2R,3R)-2,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 908nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetG-protein coupled receptor 52(Homo sapiens (Human))TBA
LigandPNGBDBM50556716(CHEMBL4796964)copy SMILES
Affinity DataIC50: 910nMAssay Description:Antagonist activity at GPR52 (unknown origin) expressed in HEK293 cells assessed as inhibition of WO459-induced cAMP accumulation preincubated for 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P9327PubMed
TargetG-protein coupled receptor 52(Homo sapiens (Human))TBA
LigandPNGBDBM50556721(CHEMBL4790746)copy SMILES
Affinity DataIC50: 1.01E+3nMAssay Description:Antagonist activity at GPR52 (unknown origin) expressed in HEK293 cells assessed as inhibition of WO459-induced cAMP accumulation preincubated for 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P9327PubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology

LigandPNGBDBM10453(Bivalent 4-Aminoquinoline 9g | N-[8-(quinolin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N50GZPubMed
TargetG-protein coupled receptor 52(Homo sapiens (Human))TBA
LigandPNGBDBM50556719(CHEMBL4782590)copy SMILES
Affinity DataIC50: 1.08E+3nMAssay Description:Antagonist activity at GPR52 (unknown origin) expressed in HEK293 cells assessed as inhibition of WO459-induced cAMP accumulation preincubated for 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P9327PubMed
TargetG-protein coupled receptor 52(Homo sapiens (Human))TBA
LigandPNGBDBM50556710(CHEMBL4741257)copy SMILES
Affinity DataIC50: 1.23E+3nMAssay Description:Antagonist activity at GPR52 (unknown origin) expressed in HEK293 cells assessed as inhibition of WO459-induced cAMP accumulation preincubated for 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P9327PubMed
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