Compile Data Set for Download or QSAR
Found 68 with Last Name = 'hui' and Initial = 'yh'
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243396(CHEMBL1231520)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of human AICARFTMore data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)copy SMILEScopy InChI
Affinity DataKi:  180nMAssay Description:Binding constant at colchicine site of bovine brain tubulinMore data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50109343(1-Methyl-5-[(S)-5-(3,4,5-trimethoxy-phenyl)-4,5-di...)copy SMILEScopy InChI
Affinity DataKi:  630nMAssay Description:Binding constant at colchicine site of bovine brain tubulinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32W7PubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)copy SMILEScopy InChI
Affinity DataKi:  780nMAssay Description:Binding constant at colchicine site of bovine brain tubulinMore data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50109342(1-Methyl-5-[(R)-5-(3,4,5-trimethoxy-phenyl)-4,5-di...)copy SMILEScopy InChI
Affinity DataKi:  3.69E+3nMAssay Description:Binding constant at colchicine site of bovine brain tubulinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32W7PubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50012278((2ALPHA,2''BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLAS...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Binding constant at colchicine site of bovine brain tubulinMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243463(CHEMBL4100363)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243462(CHEMBL4083899)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243461(CHEMBL4075503)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243486(CHEMBL4081385)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243487(CHEMBL4091668)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243441(CHEMBL4076500)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243443(CHEMBL4070790)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243485(CHEMBL4074469)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243415(CHEMBL4063104)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243434(CHEMBL4079085)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243442(CHEMBL4099409)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243433(CHEMBL4101204)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243477(CHEMBL4092503)copy SMILEScopy InChI
Affinity DataIC50: 608nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111568(2-Methoxy-5-[5-(3,4,5-trimethoxy-phenyl)-3H-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 680nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243414(CHEMBL4084757)copy SMILEScopy InChI
Affinity DataIC50: 723nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111579(2-Methoxy-5-[5-(3,4,5-trimethoxy-phenyl)-3H-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111574(1-Methyl-5-[4-(3,4,5-trimethoxy-phenyl)-oxazol-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111554(CHEMBL296066 | Dimethyl-{4-[4-(3,4,5-trimethoxy-ph...)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111558(2-Methoxy-5-[4-(3,4,5-trimethoxy-phenyl)-oxazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111567(2-Methoxy-5-[4-(3,4,5-trimethoxy-phenyl)-oxazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 980nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243396(CHEMBL1231520)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111566(1-Methyl-6-[5-(3,4,5-trimethoxy-phenyl)-3H-imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111555(1-Methyl-5-[3-(3,4,5-trimethoxy-phenyl)-3H-imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111569(1-Methyl-6-[3-methyl-5-(3,4,5-trimethoxy-phenyl)-3...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111580(5-(4-Methoxy-phenyl)-4-(3,4,5-trimethoxy-phenyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50109351(1-[5-(4-Amino-3-methyl-phenyl)-2-(3,4,5-trimethoxy...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Activity towards binding at colchicine site of bovine brain tubulinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC32W7PubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111570(CHEMBL296406 | Dimethyl-{4-[5-(3,4,5-trimethoxy-ph...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111578(2-Methoxy-5-[3-(3,4,5-trimethoxy-phenyl)-3H-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111562(2-Methoxy-5-[3-(3,4,5-trimethoxy-phenyl)-3H-imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 7.70E+3nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243413(CHEMBL4077027)copy SMILEScopy InChI
Affinity DataIC50: 1.81E+4nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111556(CHEMBL297236 | Dimethyl-{4-[3-(3,4,5-trimethoxy-ph...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111559(2-Methoxy-5-[3-methyl-5-(3,4,5-trimethoxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243508(CHEMBL4101760)copy SMILEScopy InChI
Affinity DataIC50: 3.48E+4nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111561(CHEMBL47112 | Dimethyl-{4-[1-(3,4,5-trimethoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111582(1-Methyl-5-[3-(3,4,5-trimethoxy-phenyl)-3H-imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111565(5-[3-(3,4,5-Trimethoxy-phenyl)-3H-imidazol-4-yl]-1...)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+4nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7GKQPubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243397(CHEMBL4100255)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243398(CHEMBL4082237)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243415(CHEMBL4063104)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MTHFD2 (unknown origin) using NAD/5,10-methylene THF as substrate after 30 mins by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
LigandPNGBDBM50243415(CHEMBL4063104)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MTHFD2L (unknown origin) using NAD/5,10-methylene THF as substrate after 2 hrs by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetC-1-tetrahydrofolate synthase, cytoplasmic(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243415(CHEMBL4063104)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MTHFD1 (unknown origin) using NADP/5,10-methylene THF as substrate after 30 mins by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243415(CHEMBL4063104)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SHMT1 (unknown origin) using serine/THF as substrate after 50 mins by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243415(CHEMBL4063104)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of thymidylate synthase (unknown origin) using dUMP/5,10-methylene THF as substrate after 1 hr by mass spectrometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222X6JPubMed
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