Compile Data Set for Download or QSAR
Found 37 with Last Name = 'liao' and Initial = 'yh'
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibition of recombinant human full-length C-terminal FLAG-His tagged HDAC1 (1 to 482 residues) expressed in Sf21 insect cells using RHK-K(Ac)-AMC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibition of recombinant human C-terminal GST-tagged HDAC2 (1 to 488 residues) expressed in baculovirus infected insect cells using RHKKAc-AMC as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Inhibition of human recombinant HDAC3/NCOR2 using RHKKAc-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50551593(CHEMBL4749443)copy SMILES
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of recombinant human full-length C-terminal FLAG-His tagged HDAC1 (1 to 482 residues) expressed in Sf21 insect cells using RHK-K(Ac)-AMC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50551596(CHEMBL4788251)copy SMILES
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of recombinant human full-length C-terminal FLAG-His tagged HDAC1 (1 to 482 residues) expressed in Sf21 insect cells using RHK-K(Ac)-AMC a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50551593(CHEMBL4749443)copy SMILES
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of recombinant human C-terminal GST-tagged HDAC2 (1 to 488 residues) expressed in baculovirus infected insect cells using RHKKAc-AMC as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
LigandPNGBDBM50551595(CHEMBL4757836)copy SMILES
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of human recombinant HDAC3/NCOR2 using RHKKAc-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
LigandPNGBDBM50551593(CHEMBL4749443)copy SMILES
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of human recombinant HDAC3/NCOR2 using RHKKAc-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
LigandPNGBDBM50551596(CHEMBL4788251)copy SMILES
Affinity DataIC50: 2.55E+3nMAssay Description:Inhibition of human recombinant HDAC3/NCOR2 using RHKKAc-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50551594(CHEMBL4777009)copy SMILES
Affinity DataIC50: 4.95E+3nMAssay Description:Inhibition of recombinant human C-terminal GST-tagged HDAC2 (1 to 488 residues) expressed in baculovirus infected insect cells using RHKKAc-AMC as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50551594(CHEMBL4777009)copy SMILES
Affinity DataIC50: 5.45E+3nMAssay Description:Inhibition of recombinant human full-length C-terminal FLAG-His tagged HDAC1 (1 to 482 residues) expressed in Sf21 insect cells using RHK-K(Ac)-AMC a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
LigandPNGBDBM50551594(CHEMBL4777009)copy SMILES
Affinity DataIC50: 7.92E+3nMAssay Description:Inhibition of human recombinant HDAC3/NCOR2 using RHKKAc-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50551595(CHEMBL4757836)copy SMILES
Affinity DataIC50: 9.08E+3nMAssay Description:Inhibition of recombinant human C-terminal GST-tagged HDAC2 (1 to 488 residues) expressed in baculovirus infected insect cells using RHKKAc-AMC as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)copy SMILEScopy InChI
Affinity DataIC50: 9.88E+3nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50551596(CHEMBL4788251)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human C-terminal GST-tagged HDAC2 (1 to 488 residues) expressed in baculovirus infected insect cells using RHKKAc-AMC as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50551595(CHEMBL4757836)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal FLAG-His tagged HDAC1 (1 to 482 residues) expressed in Sf21 insect cells using RHK-K(Ac)-AMC a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50551595(CHEMBL4757836)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50551596(CHEMBL4788251)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50551593(CHEMBL4749443)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50551594(CHEMBL4777009)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAc-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T72N3FPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50565261(CHEMBL4782890)copy SMILES
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal Hsi-tagged HSP90alpha (1 to 732 residues) expressed in Escherichia coli measured after 2 to 3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7ZR6PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50565260(CHEMBL4778390)copy SMILES
Affinity DataIC50: 4.09E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal Hsi-tagged HSP90alpha (1 to 732 residues) expressed in Escherichia coli measured after 2 to 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7ZR6PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal Hsi-tagged HSP90alpha (1 to 732 residues) expressed in Escherichia coli measured after 2 to 3 ...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50565267(CHEMBL4787861)copy SMILES
Affinity DataIC50: 4.49E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal Hsi-tagged HSP90alpha (1 to 732 residues) expressed in Escherichia coli measured after 2 to 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7ZR6PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50565264(CHEMBL4794274)copy SMILES
Affinity DataIC50: 4.53E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal Hsi-tagged HSP90alpha (1 to 732 residues) expressed in Escherichia coli measured after 2 to 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7ZR6PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50565263(CHEMBL4778950)copy SMILES
Affinity DataIC50: 4.53E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal Hsi-tagged HSP90alpha (1 to 732 residues) expressed in Escherichia coli measured after 2 to 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7ZR6PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50565268(CHEMBL4778357)copy SMILES
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal Hsi-tagged HSP90alpha (1 to 732 residues) expressed in Escherichia coli measured after 2 to 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7ZR6PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50565262(CHEMBL4786291)copy SMILES
Affinity DataIC50: 4.82E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal Hsi-tagged HSP90alpha (1 to 732 residues) expressed in Escherichia coli measured after 2 to 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7ZR6PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50241571(CHEMBL485981 | buddledin A)copy SMILEScopy InChI
Affinity DataIC50: 5.04E+4nMAssay Description:Inhibition of 5-lipoxygenase in Wistar rat peritoneal leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1JCWPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50565269(CHEMBL4783186)copy SMILES
Affinity DataIC50: 5.44E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal Hsi-tagged HSP90alpha (1 to 732 residues) expressed in Escherichia coli measured after 2 to 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7ZR6PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50565265(CHEMBL4778594)copy SMILES
Affinity DataIC50: 5.47E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal Hsi-tagged HSP90alpha (1 to 732 residues) expressed in Escherichia coli measured after 2 to 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7ZR6PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM20800(2-amino-6-halopurine analogue, 20 | 6-chloro-9-[(4...)copy SMILEScopy InChI
Affinity DataIC50: 5.68E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal Hsi-tagged HSP90alpha (1 to 732 residues) expressed in Escherichia coli measured after 2 to 3 ...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50565266(CHEMBL4783269)copy SMILES
Affinity DataIC50: 5.88E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal Hsi-tagged HSP90alpha (1 to 732 residues) expressed in Escherichia coli measured after 2 to 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7ZR6PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM23415(5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+5nMAssay Description:Inhibition of 5-lipoxygenase in Wistar rat peritoneal leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1JCWPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50241572(CHEMBL519046 | buddledin B)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of 5-lipoxygenase in Wistar rat peritoneal leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1JCWPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50250796(CHEMBL465682 | buddledin C)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of 5-lipoxygenase in Wistar rat peritoneal leukocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1JCWPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50565259(CHEMBL4780581)copy SMILES
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of recombinant human full-length C-terminal Hsi-tagged HSP90alpha (1 to 732 residues) expressed in Escherichia coli measured after 2 to 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7ZR6PubMed