Compile Data Set for Download or QSAR
Found 30 with Last Name = 'choe' and Initial = 'ys'
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50195684(1-[4-(3-fluoropropoxy)-3-methoxyphenyl]-5-hydroxy-...)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Displacement of [125I]IMSB from beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38TB2PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100131(5-(Biphenyl-4-ylazo)-bis (2-hydroxy-benzoic acid)(...)copy SMILEScopy InChI
Affinity DataKi:  0.160nMAssay Description:Displacement of [125I]IMSB from beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38TB2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50063266(6-Nitro-2-piperazin-1-yl-quinoline | 6-nitroquipaz...)copy SMILEScopy InChI
Affinity DataKi:  0.170nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50067040(((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...)copy SMILEScopy InChI
Affinity DataKi:  0.208nMAssay Description:Displacement of [125I]IMSB from beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38TB2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)copy SMILEScopy InChI
Affinity DataKi:  0.530nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090213(6-Bromo-2-piperazin-1-yl-quinoline | CHEMBL39164)copy SMILEScopy InChI
Affinity DataKi:  0.910nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50173647((E)-4-(4-(methylamino)styryl)phenol | 4-(4-(methyl...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Binding affinity to amyloid beta (1-42) aggregates in human Alzheimer's disease brain sectionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92F5GPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090216(6-Chloro-2-piperazin-1-yl-quinoline | CHEMBL290537)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090215(2-[1,4]Diazepan-1-yl-6-nitro-quinoline | CHEMBL431...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50485236(BAY-949172 | CHEBI:79033 | FLORBETABEN F18 | Florb...)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:Binding affinity to amyloid beta (1-42) aggregates in human Alzheimer's disease brain sectionsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92F5GPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50484946((18F)AV-45 | 18F-AV-45 | AV-45 F-18 | Amyvid | CHE...)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Binding affinity to amyloid beta (1-42) aggregates in human Alzheimer's disease brain sectionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92F5GPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090210(6-Iodo-2-piperazin-1-yl-quinoline | CHEMBL38466)copy SMILEScopy InChI
Affinity DataKi:  6.60nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090217(CHEMBL39265 | N,N'-Dimethyl-N-(6-nitro-quinolin-2-...)copy SMILEScopy InChI
Affinity DataKi:  8.40nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50195683(5-hydroxy-1-(4-hydroxy-3-iodo-5-methoxyphenyl)-7-(...)copy SMILEScopy InChI
Affinity DataKi:  9.37nMAssay Description:Displacement of [125I]IMSB from beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38TB2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090214(3-Bromo-6-nitro-2-piperazin-1-yl-quinoline | CHEMB...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50195682(4-(4-hydroxy-3-iodo-5-methoxyphenyl)-3-buten-2-one...)copy SMILEScopy InChI
Affinity DataKi:  20.0nMAssay Description:Displacement of [125I]IMSB from beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38TB2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090211(2-(3-Methyl-piperazin-1-yl)-6-nitro-quinoline | CH...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50195681(5-hydroxy-1-(4-hydroxy-3-iodo-5-methoxyphenyl)-1,4...)copy SMILEScopy InChI
Affinity DataKi:  24.9nMAssay Description:Displacement of [125I]IMPY from beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38TB2PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50195682(4-(4-hydroxy-3-iodo-5-methoxyphenyl)-3-buten-2-one...)copy SMILEScopy InChI
Affinity DataKi:  36.6nMAssay Description:Displacement of [125I]IMPY from beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38TB2PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50195679((E)-4-(4-Hydroxy-3-methoxy-phenyl)-but-3-en-2-one ...)copy SMILEScopy InChI
Affinity DataKi:  54.2nMAssay Description:Displacement of [125I]IMSB from beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38TB2PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50195679((E)-4-(4-Hydroxy-3-methoxy-phenyl)-but-3-en-2-one ...)copy SMILEScopy InChI
Affinity DataKi:  55.9nMAssay Description:Displacement of [125I]IMPY from beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38TB2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50014407(2-(piperazin-1-yl)quinoline | 2-Piperazin-1-yl-qui...)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090212(CHEMBL38754 | N*1*-(6-Nitro-quinolin-2-yl)-ethane-...)copy SMILEScopy InChI
Affinity DataKi:  164nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50195680(4-[4-(2-fluoroethoxy)-3-methoxyphenyl]-3-buten-2-o...)copy SMILEScopy InChI
Affinity DataKi:  233nMAssay Description:Displacement of [125I]IMPY from beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38TB2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090218(6,8-Dinitro-2-piperazin-1-yl-quinoline | CHEMBL377...)copy SMILEScopy InChI
Affinity DataKi:  313nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50195685(1-[4-(3-fluoropropoxy)-3-methoxyphenyl]-5-hydroxy-...)copy SMILEScopy InChI
Affinity DataKi:  316nMAssay Description:Displacement of [125I]IMPY from beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38TB2PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50195687(4-[4-(3-fluoropropoxy)-3-methoxyphenyl]-3-buten-2-...)copy SMILEScopy InChI
Affinity DataKi:  839nMAssay Description:Displacement of [125I]IMPY from beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38TB2PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50195686(1-[4-(2-fluoroethoxy)-3-methoxyphenyl]-5-hydroxy-1...)copy SMILEScopy InChI
Affinity DataKi:  958nMAssay Description:Displacement of [125I]IMPY from beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38TB2PubMed