Compile Data Set for Download or QSAR
Found 359 with Last Name = 'wang' and Initial = 'yt'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)copy SMILEScopy InChI
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM97563(US8470825, 4i)copy SMILEScopy InChI
Affinity DataKi:  50nMMore data for this Ligand-Target Pair
In DepthDetails
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))TBA
LigandPNGBDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)copy SMILEScopy InChI
Affinity DataIC50: 0.110nMMore data for this Ligand-Target Pair
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50084621(BMN 673 | Talazoparib)copy SMILEScopy InChI
Affinity DataIC50: 0.570nMMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)copy SMILEScopy InChI
Affinity DataIC50: 0.830nMMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM139658(US8894989, 37)copy SMILEScopy InChI
In DepthDetails
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))TBA
LigandPNGBDBM139658(US8894989, 37)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
In DepthDetails
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50536939(CHEMBL4569417)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50536939(CHEMBL4569417)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167952(1-(4-(3-Methoxyphenyl)piperazin-1-yl)-3-(quinazoli...)copy SMILEScopy InChI
Affinity DataIC50: 2.89nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM4994((3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)c...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Influenza A Jinan/15/90 H3N2 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM50331095(CHEMBL1289494 | Tivozanib | US10464902, Tivozanib)copy SMILEScopy InChI
Affinity DataIC50: 3.38nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167953(1-(4-(4-Methoxyphenyl)piperazin-1-yl)-3-(quinazoli...)copy SMILEScopy InChI
Affinity DataIC50: 3.42nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167954(1-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 4.98nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50288530(CHEMBL4098253)copy SMILEScopy InChI
In DepthDetails
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50613638(CEP-9722 | Cep 9722 | Cep-9722)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167956(1-(4-(3,4-Dichlorophenyl)piperazin-1-yl)-3-(quinaz...)copy SMILEScopy InChI
Affinity DataIC50: 8.42nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167951(1-(4-(2-Methoxyphenyl)piperazin-1-yl)-3-(quinazoli...)copy SMILEScopy InChI
Affinity DataIC50: 9.98nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167957(1-(4-(2,4-Dimethylphenyl)piperazin-1-yl)-3-(quinaz...)copy SMILEScopy InChI
Affinity DataIC50: 12.4nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM4994((3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)c...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of Influenza A PR/8/34 H1N1 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50613639(CHEMBL190434)copy SMILES
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant CA2 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Bos taurus)TBA
LigandPNGBDBM27709(2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin...)copy SMILEScopy InChI
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167950(1-(4-(4-Nitrophenyl)piperazin-1-yl)-3-(quinazolin-...)copy SMILEScopy InChI
Affinity DataIC50: 16.5nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50613638(CEP-9722 | Cep 9722 | Cep-9722)copy SMILES
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167949(1-(4-(4-Fluorophenyl)piperazin-1-yl)-3-(quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 21.8nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50492595(CHEMBL2408077)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant CA2 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61P55PubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50492590(CHEMBL2408085)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant CA9 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61P55PubMed
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50006932(CHEMBL3237245)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of Keap1 Kelch domain (unknown origin) /Nrf2 (unknown origin) interaction using fluorescein-labeled 9-mer peptide containing NRF2 Neh2 dom...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G163CRPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50492592(CHEMBL2408078)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant CA2 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61P55PubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant CA9 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61P55PubMed
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50440135(CHEMBL2426395)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of CDK6 (unknown origin) using histone H1 as substrate after 10 mins in presence of [gamma-32P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0HKHPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167945(1-(4-Phenylpiperazin-1-yl)-3-(quinazolin-4-yloxy)p...)copy SMILEScopy InChI
Affinity DataIC50: 32.6nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50440136(CHEMBL2426391)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of CDK6 (unknown origin) using histone H1 as substrate after 10 mins in presence of [gamma-32P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0HKHPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50492599(CHEMBL2408074)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant CA2 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61P55PubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50492593(CHEMBL2408080)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant CA9 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61P55PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167948(1-(4-(2-Fluorophenyl)piperazin-1-yl)-3-(quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 34.7nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50440137(CHEMBL2426387)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of CDK6 (unknown origin) using histone H1 as substrate after 10 mins in presence of [gamma-32P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0HKHPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM50331095(CHEMBL1289494 | Tivozanib | US10464902, Tivozanib)copy SMILEScopy InChI
Affinity DataIC50: 42.4nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50440138(CHEMBL2426383)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of CDK6 (unknown origin) using histone H1 as substrate after 10 mins in presence of [gamma-32P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0HKHPubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50492588(CHEMBL2408084)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant CA9 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61P55PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM27496((4Z)-4-[(1-methyl-1H-pyrrol-2-yl)methylidene]-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 45nMMore data for this Ligand-Target Pair
In DepthDetails
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167947(1-(4-(3-Chlorophenyl)piperazin-1-yl)-3-(quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 47.4nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167955(1-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-(quinaz...)copy SMILEScopy InChI
Affinity DataIC50: 47.7nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50492600(CHEMBL2408073)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant CA9 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61P55PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167946(1-(4-(2-Chlorophenyl)piperazin-1-yl)-3-(quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 49.8nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50440139(CHEMBL2426399)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of CDK6 (unknown origin) using histone H1 as substrate after 10 mins in presence of [gamma-32P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0HKHPubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50492598(CHEMBL2408088)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant CA9 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61P55PubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50492597(CHEMBL2408081)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant CA9 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61P55PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50492594(CHEMBL2408079)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant CA2 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61P55PubMed
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