Compile Data Set for Download or QSAR
Found 108 with Last Name = 'wu' and Initial = 'yt'
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59242(Benzotriazole ester, 8 | acs.jmedchem.1c00409_ST.6...)copy SMILEScopy InChI
Affinity DataKi:  7.5nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59240(Benzotriazole ester, 6 | acs.jmedchem.1c00409_ST.8)copy SMILEScopy InChI
Affinity DataKi:  11.1nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1V9GPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59239(Benzotriazole ester, 5 | acs.jmedchem.1c00409_ST.9)copy SMILEScopy InChI
Affinity DataKi:  12.1nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1V9GPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59243(Benzotriazole ester, 9 | acs.jmedchem.1c00409_ST.1...)copy SMILEScopy InChI
Affinity DataKi:  12.3nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1V9GPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59244(Benzotriazole ester, 10 | acs.jmedchem.1c00409_ST....)copy SMILEScopy InChI
Affinity DataKi:  13.8nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1V9GPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59238(Benzotriazole ester, 4 | acs.jmedchem.1c00409_ST.1...)copy SMILEScopy InChI
Affinity DataKi:  17.4nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1V9GPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59237(Benzotriazole ester, 3 | acs.jmedchem.1c00409_ST.1...)copy SMILEScopy InChI
Affinity DataKi:  19.5nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1V9GPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59241(Benzotriazole ester, 7)copy SMILEScopy InChI
Affinity DataKi:  22.9nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1V9GPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM11234((2S)-N-(2-chloro-4-nitrophenyl)-2-{[4-(dimethylami...)copy SMILEScopy InChI
Affinity DataKi:  30nM ΔG°:  -42.9kJ/mole IC50: 60nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26S1PubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119876(SL932 | US9073941, 503)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K48X6PubMed
TargetPrephenate dehydrogenase(Mycobacterium tuberculosis H37Rv)
Weill Cornell Medical College

LigandPNGBDBM119876(SL932 | US9073941, 503)copy SMILEScopy InChI
Affinity DataKi:  78nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K48X6PubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119877(SL809 | US9073941, 502)copy SMILEScopy InChI
Affinity DataKi:  93nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K48X6PubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119878(SL827 | US9073941, 500)copy SMILEScopy InChI
Affinity DataKi:  140nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119880(SL418)copy SMILEScopy InChI
Affinity DataKi:  143nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K48X6PubMed
TargetPrephenate dehydrogenase(Mycobacterium tuberculosis H37Rv)
Weill Cornell Medical College

LigandPNGBDBM119878(SL827 | US9073941, 500)copy SMILEScopy InChI
Affinity DataKi:  155nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K48X6PubMed
TargetPrephenate dehydrogenase(Mycobacterium tuberculosis H37Rv)
Weill Cornell Medical College

LigandPNGBDBM119877(SL809 | US9073941, 502)copy SMILEScopy InChI
Affinity DataKi:  155nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K48X6PubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119879(SL917 | US9073941, 505)copy SMILEScopy InChI
Affinity DataKi:  233nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K48X6PubMed
TargetPrephenate dehydrogenase(Mycobacterium tuberculosis H37Rv)
Weill Cornell Medical College

LigandPNGBDBM119879(SL917 | US9073941, 505)copy SMILEScopy InChI
Affinity DataKi:  289nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K48X6PubMed
TargetPrephenate dehydrogenase(Mycobacterium tuberculosis H37Rv)
Weill Cornell Medical College

LigandPNGBDBM119880(SL418)copy SMILEScopy InChI
Affinity DataKi:  333nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K48X6PubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM11261(dipeptidomimetic unsaturated ester 18c | ethyl (2E...)copy SMILEScopy InChI
Affinity DataKi:  520nM ΔG°:  -35.9kJ/mole IC50: 1.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1Q9RPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59246(Benzotriazole ester, 14)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1V9GPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM11240(Anilide Inhibitor 4k | N-[(benzyloxy)carbonyl]-L-v...)copy SMILEScopy InChI
Affinity DataKi:  1.51E+3nM ΔG°:  -33.2kJ/mole IC50: 6.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26S1PubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM11239((2S)-N-[(1S)-1-{[(1S,2S)-1-{[(1S)-1-[(2-chloro-4-n...)copy SMILEScopy InChI
Affinity DataKi:  1.61E+3nM ΔG°:  -33.1kJ/mole IC50: 5.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26S1PubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM11236((2S)-N-[(1S)-1-[(2-chloro-4-nitrophenyl)carbamoyl]...)copy SMILEScopy InChI
Affinity DataKi:  2.29E+3nM ΔG°:  -32.2kJ/mole IC50: 5.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26S1PubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM11260(dipeptidomimetic unsaturated ester 18b | ethyl (2E...)copy SMILEScopy InChI
Affinity DataKi:  2.48E+3nM ΔG°:  -32.0kJ/mole IC50: 5.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1Q9RPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM11237((2S)-N-[(1S)-1-{[(1S)-1-[(2-chloro-4-nitrophenyl)c...)copy SMILEScopy InChI
Affinity DataKi:  2.90E+3nM ΔG°:  -31.6kJ/mole IC50: 7.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26S1PubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM11263(dipeptidomimetic unsaturated ester 18e | ethyl (2E...)copy SMILEScopy InChI
Affinity DataKi:  3.05E+3nM ΔG°:  -31.5kJ/mole IC50: 7.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1Q9RPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM11241((2S)-N,N'-bis[(1S)-1-[(2-chloro-4-nitrophenyl)carb...)copy SMILEScopy InChI
Affinity DataKi:  3.10E+3nM ΔG°:  -31.4kJ/mole IC50: 4.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26S1PubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM11238((2S)-N-[(1S)-1-{[(1S)-1-[(2-chloro-4-nitrophenyl)c...)copy SMILEScopy InChI
Affinity DataKi:  4.30E+3nM ΔG°:  -30.6kJ/mole IC50: 5.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26S1PubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59249(Benzotriazole ester, 17 | acs.jmedchem.1c00409_ST....)copy SMILEScopy InChI
Affinity DataKi:  4.50E+3nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1V9GPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM11259(dipeptidomimetic unsaturated ester 18a | ethyl (2E...)copy SMILEScopy InChI
Affinity DataKi:  6.44E+3nM ΔG°:  -29.6kJ/mole IC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1Q9RPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59250(Benzotriazole ester, 18 | acs.jmedchem.1c00409_ST....)copy SMILEScopy InChI
Affinity DataKi:  6.70E+3nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1V9GPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM11262(dipeptidomimetic unsaturated ester 18d | ethyl (2E...)copy SMILEScopy InChI
Affinity DataKi:  9.05E+3nM ΔG°:  -28.8kJ/mole IC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1Q9RPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59251(Benzotriazole ester, 19)copy SMILEScopy InChI
Affinity DataKi: >5.00E+4nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1V9GPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Academia Sinica

LigandPNGBDBM59252(Benzotriazole ester, 20)copy SMILEScopy InChI
Affinity DataKi: >5.00E+4nMpH: 7.5Assay Description:Inhibition assay against SARS-CoV 3CL protease, a fluorometric assay was utilized to determine the inhibition constants of the samples.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1V9GPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center for Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223090(3-(4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VT1PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center for Biotechnology

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center for Biotechnology

Curated by ChEMBL
LigandPNGBDBM50095259((6,7-Dimethoxy-quinazolin-4-yl)-(3-ethynyl-phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VT1PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center for Biotechnology

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center for Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223084(CHEMBL251498 | N-(3-chloro-4-fluorophenyl)-6-(3-mo...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VT1PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center for Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223082(CHEMBL251700 | N-(3-chloro-4-fluorophenyl)-6-(3-(p...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VT1PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center for Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223095(4-(4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VT1PubMed
TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandPNGBDBM119881(K906-3584)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K48X6PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center for Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223092(5-(4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl...)copy SMILEScopy InChI
Affinity DataIC50: 114nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VT1PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center for Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223085(CHEMBL249509 | N-(3-chloro-4-fluorophenyl)-6-ethyn...)copy SMILEScopy InChI
Affinity DataIC50: 127nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VT1PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center for Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223093(4-(4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl...)copy SMILEScopy InChI
Affinity DataIC50: 152nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VT1PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center for Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223088(4-(4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl...)copy SMILEScopy InChI
Affinity DataIC50: 186nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VT1PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center for Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223086(4-(3-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 206nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VT1PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center for Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223094(CHEMBL249511 | N-(3-chloro-4-fluorophenyl)-6-(2-ph...)copy SMILEScopy InChI
Affinity DataIC50: 331nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VT1PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Development Center for Biotechnology

Curated by ChEMBL
LigandPNGBDBM50223091(4-(3-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)but...)copy SMILEScopy InChI
Affinity DataIC50: 402nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VT1PubMed
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