Compile Data Set for Download or QSAR
Found 39 with Last Name = 'caringal' and Initial = 'yv'
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50358043(CHEMBL1794051 | GW-5074)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095423(5-tert-Butyl-3-(3-phenyl-ureido)-thiophene-2-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105619(1-(5-tert-Butyl-isoxazol-3-yl)-3-(4-phenoxy-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of Escherichia coli derived Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105619(1-(5-tert-Butyl-isoxazol-3-yl)-3-(4-phenoxy-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105601(5-tert-Butyl-3-[3-(5-methyl-[1,3,4]thiadiazol-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095399(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105621(5-tert-Butyl-3-[3-(5-cyclopropyl-[1,3,4]thiadiazol...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105597(5-tert-Butyl-3-[3-(5-ethyl-[1,3,4]thiadiazol-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095396(5-tert-Butyl-3-(3-p-tolyl-ureido)-furan-2-carboxyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095428(5-tert-Butyl-3-(3-p-tolyl-ureido)-1H-pyrrole-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105606(5-tert-Butyl-3-[3-(4-methyl-thiophen-2-yl)-ureido]...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105620(5-tert-Butyl-3-[3-(5-methyl-thiophen-2-yl)-ureido]...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105612(5-Isopropyl-3-(3-p-tolyl-ureido)-thiophene-2-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095403(1-(5-tert-butyl-2-(methylcarbamoyl)thiophen-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105599(5-Bromomethyl-3-(3-p-tolyl-ureido)-thiophene-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095414(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105615(5-tert-Butyl-3-[3-(5-trifluoromethyl-[1,3,4]thiadi...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105613(5-tert-Butyl-3-[3-(1-methyl-1H-pyrazol-3-yl)-ureid...)copy SMILEScopy InChI
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095420(5-tert-Butyl-3-[3-(4-chloro-phenyl)-ureido]-thioph...)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105598(5-tert-Butyl-3-[3-(1-ethyl-1H-pyrrol-3-yl)-ureido]...)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095394(5-tert-Butyl-3-[3-(3,4-dichloro-phenyl)-ureido]-fu...)copy SMILEScopy InChI
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105596(5-tert-Butyl-3-[3-(1-ethyl-1H-pyrazol-3-yl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105614(5-tert-Butyl-3-[3-(1-isopropyl-1H-pyrrol-3-yl)-ure...)copy SMILEScopy InChI
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105604(5-tert-Butyl-3-[3-(5-tert-butyl-[1,3,4]thiadiazol-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105602(5-tert-Butyl-3-[3-(1-propyl-1H-pyrrol-3-yl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105610(5-tert-Butyl-3-(3-thiophen-2-yl-ureido)-thiophene-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105617(3-[3-(1-Benzyl-1H-pyrazol-3-yl)-ureido]-5-tert-but...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105607(5-tert-Butyl-3-[3-(3,4-dichloro-phenyl)-ureido]-1H...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105611(1-(2-(aminomethyl)-5-tert-butylthiophen-3-yl)-3-p-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095411(5-tert-Butyl-3-[3-(4-hydroxy-phenyl)-ureido]-thiop...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105600(5-tert-Butyl-3-[3-(3,4-dimethyl-phenyl)-ureido]-th...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105618(1-(5-tert-butyl-2-(dimethylcarbamoyl)thiophen-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105608(5-tert-Butyl-3-[3-(1-isopropyl-1H-pyrazol-3-yl)-ur...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095423(5-tert-Butyl-3-(3-phenyl-ureido)-thiophene-2-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095395(3-[3-(4-Amino-phenyl)-ureido]-5-tert-butyl-thiophe...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105605(5-tert-Butyl-3-[3-(1-propyl-1H-pyrazol-3-yl)-ureid...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105603(5-tert-Butyl-3-[3-(3,4-dichloro-phenyl)-ureido]-th...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105616(5-tert-Butyl-3-(3-m-tolyl-ureido)-thiophene-2-carb...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105609(5-tert-Butyl-3-[3-(3-chloro-phenyl)-ureido]-thioph...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibitory concentration against raf kinase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0VD5PubMed