Compile Data Set for Download or QSAR
Found 16 with Last Name = 'cho' and Initial = 'yw'
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50397031(CHEMBL2171190)copy SMILEScopy InChI
Affinity DataKi:  8.40E+3nMAssay Description:Competitive inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells assessed as Ki intercept using Histone H4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96R4PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50397030(CHEMBL2171189)copy SMILEScopy InChI
Affinity DataKi:  1.13E+4nMAssay Description:Competitive inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells assessed as Ki intercept using Histone H4...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96R4PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50397030(CHEMBL2171189)copy SMILEScopy InChI
Affinity DataKi:  2.97E+4nMAssay Description:Non competitive inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells assessed as Ki slope using SAM preinc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96R4PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50397031(CHEMBL2171190)copy SMILEScopy InChI
Affinity DataKi: >2.57E+5nMAssay Description:Non competitive inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells assessed as Ki slope using SAM preinc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96R4PubMed
LigandPNGBDBM50175688((4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)p...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of IKKbeta in human THP-1 cells assessed as inhibition of TNFalpha-stimulated IkappaBalpha degradation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z770TPubMed
LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)copy SMILEScopy InChI
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of IKKbeta (unknown origin) assessed as substrate phosphorylation using IkappaBalpha as substrate incubated for 1 hr in presence of ATP by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z770TPubMed
LigandPNGBDBM50559687(CHEMBL4778479)copy SMILES
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of IKKbeta (unknown origin) assessed as substrate phosphorylation using IkappaBalpha as substrate incubated for 1 hr in presence of ATP by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z770TPubMed
LigandPNGBDBM153267(5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,...)copy SMILEScopy InChI
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of IKKbeta (unknown origin) assessed as substrate phosphorylation using IkappaBalpha as substrate incubated for 1 hr in presence of ATP by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z770TPubMed
LigandPNGBDBM60996(5-[(3-carboxy-4-hydroxy-phenyl)-(3-carboxy-4-keto-...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of IKKbeta (unknown origin) assessed as substrate phosphorylation using IkappaBalpha as substrate incubated for 1 hr in presence of ATP by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z770TPubMed
LigandPNGBDBM50175688((4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)p...)copy SMILEScopy InChI
Affinity DataIC50: 6.46E+3nMAssay Description:Inhibition of IKKbeta (unknown origin) assessed as substrate phosphorylation using IkappaBalpha as substrate incubated for 1 hr in presence of ATP by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z770TPubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50397030(CHEMBL2171189)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells using Histone H4(1-20) substrate preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96R4PubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50397030(CHEMBL2171189)copy SMILEScopy InChI
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of recombinant p300 HAT domain using Histone H4(1-20) substrate assessed as inhibition of histone acetyltransferase activity after 10 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96R4PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328743(3-((4-acetamidophenyl)diazenyl)-4-hydroxy-7-(3-(5-...)copy SMILEScopy InChI
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells using Histone H4(1-20) substrate preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96R4PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50397031(CHEMBL2171190)copy SMILEScopy InChI
Affinity DataIC50: 4.17E+4nMAssay Description:Inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells using Histone H4(1-20) substrate preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96R4PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50206427(7,7'-carbonylbis(azanediyl)bis(4-hydroxynaphthalen...)copy SMILEScopy InChI
Affinity DataIC50: 7.69E+4nMAssay Description:Inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells using Histone H4(1-20) substrate preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96R4PubMed
TargetHistone H4(Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50397030(CHEMBL2171189)copy SMILEScopy InChI
Affinity DataKd:  2.38E+4nMAssay Description:Binding affinity to fluorescein-labeled Histone H4(1-20) by spectroflurometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96R4PubMed