Found 144 with Last Name = 'see' and Initial = 'yy' 
Affinity DataKi: 53nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
Affinity DataKi: 660nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of HDAC1 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
3D Structure (crystal)
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:SARS-CoV-2 3CLpro expression and purification is based on a published procedure and our modified protocol is found in the supplementary file. A highl...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:SARS-CoV-2 3CLpro expression and purification is based on a published procedure and our modified protocol is found in the supplementary file. A highl...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using Arg-His-Lys-Lys(Ac) as substrate preincubated with enzyme followed by substrate addition for 2 hrs and mea...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University of Singapore
Curated by ChEMBL
National University of Singapore
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human JAK2 using poly(Glu:Tyr)(4:1) as substrate preincubated for 20 mins followed by [gamma33P]ATP addition measured after 120 mins by...More data for this Ligand-Target Pair
