Compile Data Set for Download or QSAR
Found 678 with Last Name = 'thoreau'
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463758(CHEMBL4250302)copy SMILEScopy InChI
Affinity DataKi:  0.0560nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463741(CHEMBL4239232)copy SMILEScopy InChI
Affinity DataKi:  0.0570nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463759(CHEMBL4237636)copy SMILEScopy InChI
Affinity DataKi:  0.0630nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463739(CHEMBL4237803)copy SMILEScopy InChI
Affinity DataKi:  0.0750nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463736(CHEMBL4251203)copy SMILEScopy InChI
Affinity DataKi:  0.0970nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463756(CHEMBL4246561)copy SMILEScopy InChI
Affinity DataKi:  0.150nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463750(CHEMBL4241807)copy SMILEScopy InChI
Affinity DataKi:  0.230nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463752(CHEMBL4247370)copy SMILEScopy InChI
Affinity DataKi:  0.270nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463743(CHEMBL4241370)copy SMILEScopy InChI
Affinity DataKi:  0.270nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463753(CHEMBL4250739)copy SMILEScopy InChI
Affinity DataKi:  0.270nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463754(CHEMBL4240635)copy SMILEScopy InChI
Affinity DataKi:  0.280nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463740(CHEMBL4251365)copy SMILEScopy InChI
Affinity DataKi:  0.290nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM50606735(CHEMBL5219718 | US11731973, Example 3)copy SMILES
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463739(CHEMBL4237803)copy SMILEScopy InChI
Affinity DataKi:  0.340nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic HDAC substrate after 15 mins by fluorimetrc methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463763(CHEMBL4248374)copy SMILEScopy InChI
Affinity DataKi:  0.390nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM50606737(CHEMBL5218727 | US11731973, Example 5)copy SMILES
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataKi:  0.480nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM50606738(CHEMBL5218590 | US11731973, Example 6)copy SMILES
Affinity DataKi:  0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463751(CHEMBL4244350)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463757(CHEMBL4249385)copy SMILEScopy InChI
Affinity DataKi:  0.510nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataKi:  0.540nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463764(CHEMBL4245007)copy SMILEScopy InChI
Affinity DataKi:  0.560nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM50606740(CHEMBL5220536 | US11731973, Example 30)copy SMILES
Affinity DataKi:  0.580nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463742(CHEMBL4242292)copy SMILEScopy InChI
Affinity DataKi:  0.580nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM50606739(CHEMBL5220152 | US11731973, Example 7)copy SMILES
Affinity DataKi:  0.600nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM50606742(CHEMBL5220948 | US11731973, Example 9)copy SMILES
Affinity DataKi:  0.600nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM613740(3-(2-aminobenzoxazol-5-yl)-1-(2,2- dimethylbutyl)-...)copy SMILES
Affinity DataKi:  0.600nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463767(CHEMBL4246919)copy SMILEScopy InChI
Affinity DataKi:  0.690nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM50606736(CHEMBL5218916 | US11731973, Example 10)copy SMILES
Affinity DataKi:  0.800nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM613743(1-(2,2-dimethylpropyl)-3-(2- ethylaminobenzoxazol-...)copy SMILES
Affinity DataKi:  0.800nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetHistone deacetylase 3(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463739(CHEMBL4237803)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Inhibition of human recombinant HDAC3 using fluorogenic HDAC substrate after 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM50606741(CHEMBL5219710 | US11731973, Example 1)copy SMILES
Affinity DataKi:  0.800nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463749(CHEMBL4242426)copy SMILEScopy InChI
Affinity DataKi:  0.910nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463743(CHEMBL4241370)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic HDAC substrate after 15 mins by fluorimetrc methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM613734(3-(2-amino-6-fluorobenzoxazol-5-yl)- 1-((S)-1,3-di...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM315477(US10172858, Table 1.1 | US10172858, Table 1.22)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of human recombinant GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4E-BP1 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P272KMPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM613745((+)-3-(2-aminobenzoxazol-5-yl)-1- ((S)-2-methyl-2-...)copy SMILES
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463739(CHEMBL4237803)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Inhibition of human recombinant HDAC10 using fluorogenic HDAC substrate after 45 mins by fluorimetrc methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM613746(3-(2-aminobenzoxazol-5-yl)-1-(2,2- dimethylbut-3-y...)copy SMILES
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM613744(3-(2-aminobenzoxazol-5-yl)-1-(2,2- dimethylbut-3-e...)copy SMILES
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM613736(3-(2-amino-6-fluorobenzoxazol-5-yl)- 1-(1-methylcy...)copy SMILES
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463766(CHEMBL4242750)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM613748(3-[4,6-diamino-3-(2- aminobenzoxazol-5-yl)pyrazolo...)copy SMILES
Affinity DataKi:  1.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM613749(3-(2-aminobenzoxazol-5-yl)-1-(2- methyl-2-methylsu...)copy SMILES
Affinity DataKi:  1.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetHistone deacetylase 7(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Inhibition of human recombinant HDAC7 using fluorogenic HDAC substrate class 2a after 45 mins by fluorimetrc methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM613750(3-(2-amino-4-chlorobenzoxazol-5-yl)- 1-(2,2-dimeth...)copy SMILES
Affinity DataKi:  1.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463737(CHEMBL4238353)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM582476(5-(2-aminobenzoxazol-5-yl)-7-isobutyl-7-methyl-6, ...)copy SMILES
Affinity DataKi:  2nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The reac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP78RQUS Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM613751(3-(2-amino-6-methoxybenzoxazol-5- yl)-1-(2,2-dimet...)copy SMILES
Affinity DataKi:  2.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9G6B
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463748(CHEMBL4241014)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0484TPubMed
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