Compile Data Set for Download or QSAR
Found 101 with Last Name = 'magar' and Initial = 's'
TargetLutropin-choriogonadotropic hormone receptor(Homo sapiens (Human))
Merck Serono Geneva Research Center

Curated by ChEMBL
LigandPNGBDBM50206401(CHEMBL246321 | N-((S)-1-amino-3-(4-hydroxyphenyl)-...)copy SMILEScopy InChI
Affinity DataKi:  0.311nMAssay Description:Displacement of [125I]-hCG from LH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32B2PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061754(CHEMBL542487 | N-(2-Chloro-3,5-diethyl-phenyl)-N'-...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061768(CHEMBL553034 | N-(2-Bromo-3,5-diethyl-phenyl)-N'-(...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061773(CHEMBL552829 | N-(3,5-Diethyl-2-fluoro-phenyl)-N'-...)copy SMILEScopy InChI
Affinity DataIC50: 7.40nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061807(CHEMBL552831 | N-(3,5-Diethyl-phenyl)-N'-(3-ethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061756(CHEMBL544842 | N-(3-Bromo-phenyl)-N'-(3-ethyl-phen...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061746(CHEMBL556043 | N-(3-Ethyl-phenyl)-N'-o-tolyl-guani...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061776(CHEMBL553312 | N-(2,5-Dichloro-phenyl)-N'-(3-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061805(CHEMBL542491 | N-(2,3-Dichloro-phenyl)-N'-(3-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061806(CHEMBL543433 | N-(2,6-Dichloro-phenyl)-N'-(3-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061766(CHEMBL545310 | N-(2-Chloro-phenyl)-N'-(3-ethyl-phe...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061795(CHEMBL543427 | N-(2-Chloro-3-ethyl-5-methylsulfany...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061739(CHEMBL542736 | N-(2-Chloro-3-ethyl-5-trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061778(CHEMBL542481 | N-(2,5-Dibromo-3-ethyl-phenyl)-N'-(...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061764(CHEMBL538036 | N-(2-Ethyl-phenyl)-N'-(3-ethyl-phen...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061744(CHEMBL553749 | N-(2-Bromo-3-ethyl-5-trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061741(CHEMBL543432 | N-(4-Chloro-phenyl)-N'-(3-ethyl-phe...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061770(CHEMBL541860 | N-(3-Ethyl-phenyl)-N'-(2-isopropyl-...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061755(CHEMBL540841 | N-(3-Ethyl-2-fluoro-5-trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061783(CHEMBL554355 | N-(3-Chloro-phenyl)-N'-(3-ethyl-phe...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061745(CHEMBL543673 | N'-(2,5-Dichloro-phenyl)-N-(3-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50010747(CHEMBL543201 | CHEMBL78777 | N,N'-Bis-(3-ethyl-phe...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061762(CHEMBL542730 | N-(2-Chloro-3-ethyl-5-methyl-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061788(CHEMBL543431 | N-(3,4-Dichloro-phenyl)-N'-(3-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061794(CHEMBL539299 | N-(2,4-Dichloro-phenyl)-N'-(3-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061763(CHEMBL545545 | N'-(3,4-Dichloro-phenyl)-N-(3-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061789(CHEMBL542956 | N-(2,5-Dichloro-phenyl)-N'-(3-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061758(CHEMBL545542 | N'-(2,5-Dibromo-3-ethyl-phenyl)-N-(...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061804(CHEMBL538283 | N'-(3-Bromo-phenyl)-N-(3-ethyl-phen...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061747(CHEMBL542964 | N-(3-Ethyl-phenyl)-N-methyl-N'-phen...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061799(CHEMBL555091 | N'-(3-Chloro-phenyl)-N-(3-ethyl-phe...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061791(CHEMBL545544 | N'-(2-Chloro-3-ethyl-5-methyl-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061797(CHEMBL539549 | N'-(4-Chloro-phenyl)-N-(3-ethyl-phe...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061782(CHEMBL553167 | N-(2,5-Dichloro-phenyl)-N'-(3-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061784(CHEMBL542959 | N-(3,5-Dichloro-phenyl)-N'-(3-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061760(CHEMBL554618 | N'-(2-Chloro-phenyl)-N-(3-ethyl-phe...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061803(CHEMBL540831 | N'-(3-Ethyl-2-fluoro-5-trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50043977(CHEMBL543434 | CHEMBL91628 | N,N'-Bis-(3-ethyl-phe...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061743(CHEMBL555698 | N'-(2,3-Dichloro-phenyl)-N-(3-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066417(CHEMBL112806 | N-(4-Benzyloxy-phenyl)-N'-(4-tert-b...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061786(CHEMBL540326 | N'-(2,5-Dichloro-3-trifluoromethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061772(CHEMBL543428 | N'-(2-Chloro-3,5-diethyl-phenyl)-N-...)copy SMILEScopy InChI
Affinity DataIC50: 112nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061787(CHEMBL542238 | N'-(3,5-Diethyl-2-fluoro-phenyl)-N-...)copy SMILEScopy InChI
Affinity DataIC50: 113nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061750(CHEMBL543196 | N'-(2,5-Dibromo-3-methylsulfanyl-ph...)copy SMILEScopy InChI
Affinity DataIC50: 113nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061761(CHEMBL541848 | N'-(2,5-Dibromo-3-trifluoromethoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 113nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061774(CHEMBL543436 | N'-(2-Chloro-3-ethyl-5-trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 115nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061777(CHEMBL555099 | N'-(2-Bromo-phenyl)-N-(3-ethyl-phen...)copy SMILEScopy InChI
Affinity DataIC50: 125nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066427(CHEMBL109210 | N,N'-Bis-(4-butyl-phenyl)-guanidine)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50061742(CHEMBL554868 | N'-(2,5-Dichloro-3-methylsulfanyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensionsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G161HQPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50066420(CHEMBL112132 | N-(4-Benzyloxy-phenyl)-N'-(4-butyl-...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
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