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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50191578
((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)
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Affinity Data
Ki: 46nM
Assay Description:
Displacement of europium labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q29W0F4J
PubMed
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50191578
((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)
copy SMILES
copy InChI
Affinity Data
Ki: 55nM
Assay Description:
Displacement of europium labeled NDP-alpha-MSH from human MC1R expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q29W0F4J
PubMed
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50191578
((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)
copy SMILES
copy InChI
Affinity Data
Ki: 219nM
Assay Description:
Displacement of europium labeled NDP-alpha-MSH from human MC3R expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q29W0F4J
PubMed
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50191578
((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)
copy SMILES
copy InChI
Affinity Data
EC50: 17nM
Assay Description:
Agonist activity at human MC4R transfected in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q29W0F4J
PubMed
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50191578
((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)
copy SMILES
copy InChI
Affinity Data
EC50: 52nM
Assay Description:
Agonist activity at human MC1R transfected in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q29W0F4J
PubMed
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50191578
((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)
copy SMILES
copy InChI
Affinity Data
EC50: 593nM
Assay Description:
Agonist activity at human MC3R transfected in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q29W0F4J
PubMed