Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191578((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)copy SMILEScopy InChI
Affinity DataKi:  46nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0F4JPubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191578((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)copy SMILEScopy InChI
Affinity DataKi:  55nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0F4JPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191578((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)copy SMILEScopy InChI
Affinity DataKi:  219nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0F4JPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191578((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)copy SMILEScopy InChI
Affinity DataEC50:  17nMAssay Description:Agonist activity at human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0F4JPubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191578((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)copy SMILEScopy InChI
Affinity DataEC50:  52nMAssay Description:Agonist activity at human MC1R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0F4JPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191578((S)-N-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(nap...)copy SMILEScopy InChI
Affinity DataEC50:  593nMAssay Description:Agonist activity at human MC3R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0F4JPubMed