Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50581305(CHEMBL5085972)copy SMILES
Affinity DataKi:  195nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK2936E cell membrane measured after 16-23 hrs by 1450 microbeta trilux scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N301TQPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM50581305(CHEMBL5085972)copy SMILES
Affinity DataKi:  347nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK2936E cell membrane measured after 16-23 hrs by 1450 microbeta trilux scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N301TQPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))TBA
LigandPNGBDBM50581305(CHEMBL5085972)copy SMILES
Affinity DataKi:  3.98E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in HEK2936E cell membrane measured after 16-23 hrs by 1450 microbeta trilux scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N301TQPubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))TBA
LigandPNGBDBM50581305(CHEMBL5085972)copy SMILES
Affinity DataIC50: 1.12E+4nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC5R expressed in HEK2936E cell membrane measured after 16-23 hrs by 1450 microbeta trilux scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N301TQPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))TBA
LigandPNGBDBM50581305(CHEMBL5085972)copy SMILES
Affinity DataEC50:  40nMAssay Description:Agonist activity at human melanocortin receptor 3 expressed in human T-REx-293 cells assessed as stimulation of intracellular cAMP accumulation incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N301TQPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM50581305(CHEMBL5085972)copy SMILES
Affinity DataEC50:  60nMAssay Description:Agonist activity at human melanocortin receptor 4 expressed in human T-REx-293 cells using low doxycycline assessed as stimulation of intracellular c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N301TQPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM50581305(CHEMBL5085972)copy SMILES
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at human melanocortin receptor 4 expressed in human T-REx-293 cells using high doxycycline assessed as stimulation of intracellular ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N301TQPubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50581305(CHEMBL5085972)copy SMILES
Affinity DataEC50:  8.70nMAssay Description:Agonist activity at human melanocortin receptor 1 expressed in human T-Rex-293 cells assessed as stimulation of intracellular cAMP accumulation incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N301TQPubMed