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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
TBA
Ligand
BDBM50581305
(CHEMBL5085972)
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Affinity Data
Ki: 195nM
Assay Description:
Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK2936E cell membrane measured after 16-23 hrs by 1450 microbeta trilux scintillat...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2N301TQ
PubMed
Target
Melanocortin receptor 4
(Homo sapiens (Human))
TBA
Ligand
BDBM50581305
(CHEMBL5085972)
copy SMILES
Affinity Data
Ki: 347nM
Assay Description:
Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK2936E cell membrane measured after 16-23 hrs by 1450 microbeta trilux scintillat...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2N301TQ
PubMed
Target
Melanocortin receptor 3
(Homo sapiens (Human))
TBA
Ligand
BDBM50581305
(CHEMBL5085972)
copy SMILES
Affinity Data
Ki: 3.98E+3nM
Assay Description:
Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in HEK2936E cell membrane measured after 16-23 hrs by 1450 microbeta trilux scintillat...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2N301TQ
PubMed
Target
Melanocortin receptor 5
(Homo sapiens (Human))
TBA
Ligand
BDBM50581305
(CHEMBL5085972)
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Affinity Data
IC50: 1.12E+4nM
Assay Description:
Displacement of [125I]-NDP-alpha-MSH from human MC5R expressed in HEK2936E cell membrane measured after 16-23 hrs by 1450 microbeta trilux scintillat...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2N301TQ
PubMed
Target
Melanocortin receptor 3
(Homo sapiens (Human))
TBA
Ligand
BDBM50581305
(CHEMBL5085972)
copy SMILES
Affinity Data
EC50: 40nM
Assay Description:
Agonist activity at human melanocortin receptor 3 expressed in human T-REx-293 cells assessed as stimulation of intracellular cAMP accumulation incub...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2N301TQ
PubMed
Target
Melanocortin receptor 4
(Homo sapiens (Human))
TBA
Ligand
BDBM50581305
(CHEMBL5085972)
copy SMILES
Affinity Data
EC50: 60nM
Assay Description:
Agonist activity at human melanocortin receptor 4 expressed in human T-REx-293 cells using low doxycycline assessed as stimulation of intracellular c...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2N301TQ
PubMed
Target
Melanocortin receptor 4
(Homo sapiens (Human))
TBA
Ligand
BDBM50581305
(CHEMBL5085972)
copy SMILES
Affinity Data
EC50: 2.60nM
Assay Description:
Agonist activity at human melanocortin receptor 4 expressed in human T-REx-293 cells using high doxycycline assessed as stimulation of intracellular ...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2N301TQ
PubMed
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
TBA
Ligand
BDBM50581305
(CHEMBL5085972)
copy SMILES
Affinity Data
EC50: 8.70nM
Assay Description:
Agonist activity at human melanocortin receptor 1 expressed in human T-Rex-293 cells assessed as stimulation of intracellular cAMP accumulation incub...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2N301TQ
PubMed