Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 23 hits in this display   

TargetSomatostatin receptor type 4(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi:  70nMAssay Description:Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 4 receptor expressed in CHO cell membranes incubated for 180 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91RPPubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi:  70.3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C20XKUS Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi:  70.3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN760QUS Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi:  70.3nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50Q16US Patent
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Centrexion Therapeutics Corporation

US Patent
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi:  7.36E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C20XKUS Patent
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Centrexion Therapeutics Corporation

US Patent
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi:  7.36E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN760QUS Patent
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Centrexion Therapeutics Corporation

US Patent
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi:  7.36E+3nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50Q16US Patent
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Centrexion Therapeutics Corporation

US Patent
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi:  7.36E+3nMAssay Description:Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91RPPubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Centrexion Therapeutics Corporation

US Patent
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi: >8.71E+3nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50Q16US Patent
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Centrexion Therapeutics Corporation

US Patent
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi: >8.71E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C20XKUS Patent
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Centrexion Therapeutics Corporation

US Patent
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi: >8.71E+3nMAssay Description:Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 3 receptor expressed in CHO cell membranes incubated for 180 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91RPPubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Centrexion Therapeutics Corporation

US Patent
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi: >8.71E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN760QUS Patent
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Centrexion Therapeutics Corporation

US Patent
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi: >9.63E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN760QUS Patent
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Centrexion Therapeutics Corporation

US Patent
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi: >9.63E+3nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50Q16US Patent
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Centrexion Therapeutics Corporation

US Patent
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi: >9.63E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C20XKUS Patent
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Centrexion Therapeutics Corporation

US Patent
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi: >9.63E+3nMAssay Description:Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 2 receptor expressed in CHO cell membranes incubated for 180 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91RPPubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Centrexion Therapeutics Corporation

US Patent
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi: >9.86E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN760QUS Patent
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Centrexion Therapeutics Corporation

US Patent
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi: >9.86E+3nMAssay Description:Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C20XKUS Patent
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Centrexion Therapeutics Corporation

US Patent
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi: >9.86E+3nMAssay Description:Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 5 receptor expressed in CHO cell membranes incubated for 180 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91RPPubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Centrexion Therapeutics Corporation

US Patent
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataKi: >9.86E+3nMAssay Description:For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50Q16US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataEC50:  4.30nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50Q16US Patent
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at human somatostatin 4 receptor expressed in H4 cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91RPPubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50081059(CHEMBL3421845 | US10166214, Example 138 | US106752...)copy SMILEScopy InChI
Affinity DataEC50:  4.30nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C20XKUS Patent