Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258598(US9493490, Example 10 | US9493490, G)copy SMILEScopy InChI
Affinity DataIC50: 1.79nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258598(US9493490, Example 10 | US9493490, G)copy SMILEScopy InChI
Affinity DataIC50: 3.62nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258598(US9493490, Example 10 | US9493490, G)copy SMILEScopy InChI
Affinity DataIC50: 10.9nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258598(US9493490, Example 10 | US9493490, G)copy SMILEScopy InChI
Affinity DataIC50: 13.9nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetProtein kinase C alpha type(Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258598(US9493490, Example 10 | US9493490, G)copy SMILEScopy InChI
Affinity DataIC50: 15.6nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetGlutathione S-transferase P/Rho-associated protein kinase 1 [1-535](Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258598(US9493490, Example 10 | US9493490, G)copy SMILEScopy InChI
Affinity DataIC50: 170nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetGlutathione S-transferase P/Rho-associated protein kinase 2 [5-554](Homo sapiens (Human))
Anacor Pharmaceuticals, Inc.

US Patent
LigandPNGBDBM258598(US9493490, Example 10 | US9493490, G)copy SMILEScopy InChI
Affinity DataIC50: 170nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent