Home
About
Info
Download
WebServices
Contact
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50392432
(CHEMBL2151817)
copy SMILES
copy InChI
Affinity Data
Ki: 153nM
Assay Description:
Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in human HEK293 cells after 1 hr by scintillation counter
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2KD200S
PubMed
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50392432
(CHEMBL2151817)
copy SMILES
copy InChI
Affinity Data
EC50: 7.24nM
Assay Description:
Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilization
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2KD200S
PubMed
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50392432
(CHEMBL2151817)
copy SMILES
copy InChI
Affinity Data
EC50: 7.20nM
Assay Description:
Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilization
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2KD200S
PubMed
Target
Metabotropic glutamate receptor 1
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50392432
(CHEMBL2151817)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Positive allosteric modulation of mGluR1
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2KD200S
PubMed
Target
Metabotropic glutamate receptor 8
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50392432
(CHEMBL2151817)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Positive allosteric modulation of mGluR8
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2KD200S
PubMed
Target
Metabotropic glutamate receptor 3
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50392432
(CHEMBL2151817)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Positive allosteric modulation of mGluR3
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2KD200S
PubMed
Target
Metabotropic glutamate receptor 4
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50392432
(CHEMBL2151817)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Positive allosteric modulation of mGluR4
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2KD200S
PubMed
Target
Metabotropic glutamate receptor 6
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50392432
(CHEMBL2151817)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Positive allosteric modulation of mGluR6
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2KD200S
PubMed
Target
Metabotropic glutamate receptor 7
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50392432
(CHEMBL2151817)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Positive allosteric modulation of mGluR7
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2KD200S
PubMed
Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50392432
(CHEMBL2151817)
copy SMILES
copy InChI
Affinity Data
EC50: 70nM
Assay Description:
Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2KD200S
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50392432
(CHEMBL2151817)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Positive allosteric modulation of mGluR2
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2KD200S
PubMed