Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)copy SMILEScopy InChI
Affinity DataKi:  153nMAssay Description:Displacement of [3H]methoxyPEPy from rat mGluR5 expressed in human HEK293 cells after 1 hr by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD200SPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)copy SMILEScopy InChI
Affinity DataEC50:  7.24nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD200SPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)copy SMILEScopy InChI
Affinity DataEC50:  7.20nMAssay Description:Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD200SPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGluR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD200SPubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGluR8More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD200SPubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGluR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD200SPubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGluR4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD200SPubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGluR6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD200SPubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGluR7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD200SPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)copy SMILEScopy InChI
Affinity DataEC50:  70nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD200SPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50392432(CHEMBL2151817)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of mGluR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD200SPubMed