Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340462(CHEMBL1761870 | Cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3S0GPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340462(CHEMBL1761870 | Cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3S0GPubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340462(CHEMBL1761870 | Cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Agonist activity at human MC5 receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3S0GPubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340462(CHEMBL1761870 | Cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3S0GPubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340462(CHEMBL1761870 | Cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)copy SMILEScopy InChI
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human MC5 receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3S0GPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340462(CHEMBL1761870 | Cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)copy SMILEScopy InChI
Affinity DataEC50:  22nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3S0GPubMed