Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503462(CHEMBL4527834)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Negative allosteric modulation of rat mGlu2R expressed in HEK293 cells co-expressing Galpha15 assessed as decrease in glutamate-induced calcium mobil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125WWXPubMed
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503462(CHEMBL4527834)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Negative allosteric modulation of rat mGlu2R expressed in HEK293 cells co-expressing Galpha15 assessed as decrease in glutamate-induced calcium mobil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125WWXPubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503462(CHEMBL4527834)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of human mGlu6 receptor expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium flux...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125WWXPubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503462(CHEMBL4527834)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu4 receptor expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium flux p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125WWXPubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503462(CHEMBL4527834)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu8 receptor expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium flux p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125WWXPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503462(CHEMBL4527834)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of human mGlu1R expressed in Trex293 cells assessed as decrease in glutamate-induced calcium mobilization preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125WWXPubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503462(CHEMBL4527834)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in Trex cells co-expressing Galpha15 assessed as decrease in glutamate-induced calcium mobiliz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125WWXPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503462(CHEMBL4527834)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of human mGlu5R expressed in Trex293 cells assessed as decrease in glutamate-induced calcium mobilization preincubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125WWXPubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50503462(CHEMBL4527834)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring GIRK assessed as reduction in LPA4-induced thallium flux preinc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125WWXPubMed