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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
TGF-beta receptor type-2
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50434751
(CHEMBL2385579)
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Affinity Data
IC50: 1.40nM
Assay Description:
Inhibition of TGFBR2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2WW7K3P
PubMed
Target
Bone morphogenetic protein receptor type-1A
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50434751
(CHEMBL2385579)
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Affinity Data
IC50: 10nM
Assay Description:
Inhibition of ALK3 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2WW7K3P
PubMed
Target
Bone morphogenetic protein receptor type-2
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50434751
(CHEMBL2385579)
copy SMILES
copy InChI
Affinity Data
IC50: 16nM
Assay Description:
Inhibition of BMPR2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2WW7K3P
PubMed
Target
5'-AMP-activated protein kinase subunit beta-1
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50434751
(CHEMBL2385579)
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copy InChI
Affinity Data
IC50: 40nM
Assay Description:
Inhibition of AMPK (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2WW7K3P
PubMed
Target
Serine/threonine-protein kinase receptor R3
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50434751
(CHEMBL2385579)
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Affinity Data
IC50: 42nM
Assay Description:
Inhibition of ALK1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2WW7K3P
PubMed
Target
Activin receptor type-1
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50434751
(CHEMBL2385579)
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copy InChI
Affinity Data
IC50: 53nM
Assay Description:
Inhibition of ALK2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2WW7K3P
PubMed
Target
Bone morphogenetic protein receptor type-1B
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50434751
(CHEMBL2385579)
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copy InChI
Affinity Data
IC50: 61nM
Assay Description:
Inhibition of ALK6 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2WW7K3P
PubMed
Target
Bone morphogenetic protein 4
(Mus musculus)
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50434751
(CHEMBL2385579)
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Affinity Data
IC50: 141nM
Assay Description:
Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2WW7K3P
PubMed
Target
Activin receptor type-1B
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50434751
(CHEMBL2385579)
copy SMILES
copy InChI
Affinity Data
IC50: 5.93E+3nM
Assay Description:
Inhibition of ALK4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2WW7K3P
PubMed
Target
TGF-beta receptor type-1
(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by
ChEMBL
Ligand
BDBM50434751
(CHEMBL2385579)
copy SMILES
copy InChI
Affinity Data
IC50: 1.09E+4nM
Assay Description:
Inhibition of ALK5 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2WW7K3P
PubMed