Home
About
Info
Download
WebServices
Contact
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50165937
(Ac-YK[CEHdFRWC]-NH2 | CHEMBL412495)
copy SMILES
copy InChI
Affinity Data
Ki: 1.20nM
Assay Description:
Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2251HQZ
PubMed
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50165937
(Ac-YK[CEHdFRWC]-NH2 | CHEMBL412495)
copy SMILES
copy InChI
Affinity Data
Ki: 16nM
Assay Description:
Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-1 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2251HQZ
PubMed
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50165937
(Ac-YK[CEHdFRWC]-NH2 | CHEMBL412495)
copy SMILES
copy InChI
Affinity Data
Ki: 98nM
Assay Description:
Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-3 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2251HQZ
PubMed
Target
Melanocortin receptor 5
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50165937
(Ac-YK[CEHdFRWC]-NH2 | CHEMBL412495)
copy SMILES
copy InChI
Affinity Data
Ki: >500nM
Assay Description:
Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-5 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2251HQZ
PubMed
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50165937
(Ac-YK[CEHdFRWC]-NH2 | CHEMBL412495)
copy SMILES
copy InChI
Affinity Data
EC50: 0.100nM
Assay Description:
Agonist activity at human Melanocortin-4 receptor as peptide required for 50% maximal cAMP release (n > or =2)
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2251HQZ
PubMed