Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165937(Ac-YK[CEHdFRWC]-NH2 | CHEMBL412495)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251HQZPubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165937(Ac-YK[CEHdFRWC]-NH2 | CHEMBL412495)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251HQZPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165937(Ac-YK[CEHdFRWC]-NH2 | CHEMBL412495)copy SMILEScopy InChI
Affinity DataKi:  98nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251HQZPubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165937(Ac-YK[CEHdFRWC]-NH2 | CHEMBL412495)copy SMILEScopy InChI
Affinity DataKi: >500nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251HQZPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165937(Ac-YK[CEHdFRWC]-NH2 | CHEMBL412495)copy SMILEScopy InChI
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human Melanocortin-4 receptor as peptide required for 50% maximal cAMP release (n > or =2)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251HQZPubMed