Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetMelanocortin receptor 4(Mus musculus)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164803(CHEMBL3799955)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Displacement of 125I-NDP-MSH from mouse MC4R expressed in HEK293 cells incubated for 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2139SPubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164803(CHEMBL3799955)copy SMILEScopy InChI
Affinity DataIC50: 131nMAssay Description:Displacement of 125I-NDP-MSH from mouse MC1R expressed in HEK293 cells incubated for 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2139SPubMed
TargetMelanocortin receptor 3(Mus musculus)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164803(CHEMBL3799955)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+4nMAssay Description:Displacement of 125I-NDP-MSH from mouse MC3R expressed in HEK293 cells incubated for 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2139SPubMed
TargetMelanocortin receptor 5(Mus musculus (Mouse))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164803(CHEMBL3799955)copy SMILEScopy InChI
Affinity DataEC50:  4nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2139SPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164803(CHEMBL3799955)copy SMILEScopy InChI
Affinity DataEC50:  280nMAssay Description:Agonist activity at human FLAG-tagged MC4R expressed in HTLA cells assessed as induction of beta-arrestin recruitment after 18 hrs by Presto-tango as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5S39PubMed
TargetMelanocortin receptor 4(Mus musculus)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164803(CHEMBL3799955)copy SMILEScopy InChI
Affinity DataEC50:  7.30nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2139SPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164803(CHEMBL3799955)copy SMILEScopy InChI
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human FLAG-tagged MC4R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 2 hrs by AlphaScr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5S39PubMed
TargetMelanocyte-stimulating hormone receptor(Mus musculus)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164803(CHEMBL3799955)copy SMILEScopy InChI
Affinity DataEC50:  13nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2139SPubMed
TargetMelanocortin receptor 3(Mus musculus)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50164803(CHEMBL3799955)copy SMILEScopy InChI
Affinity DataEC50:  23nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2139SPubMed