Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 15 hits in this display   

TargetCytochrome P450 1A2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132507(CHEMBL3633943)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Effective concentration against retinoic acid receptor beta in COS-7 cells co-expressing DR5-tk-CAT reporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P80PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132507(CHEMBL3633943)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Effective concentration against retinoic acid receptor gamma in COS-7 cells co-expressing DR5-tk-CAT reporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P80PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132507(CHEMBL3633943)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Effective concentration against retinoic acid receptor alpha in COS-7 cells co-expressing DR5-tk-CAT reporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P80PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132507(CHEMBL3633943)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Effective concentration against retinoic acid receptor gamma in COS-7 cells co-expressing DR5-tk-CAT reporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P80PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132507(CHEMBL3633943)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration against retinoic acid receptor gamma in COS-7 cells co-expressing DR5-tk-CAT reporter; value range (0.1-0.3)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P80PubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132507(CHEMBL3633943)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro binding affinity for PPAR-alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P80PubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132507(CHEMBL3633943)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro binding affinity for PPAR-alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P80PubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132507(CHEMBL3633943)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro binding affinity for PPAR-alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P80PubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132507(CHEMBL3633943)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro binding affinity for PPAR-gammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P80PubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132507(CHEMBL3633943)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration against human PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P80PubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132507(CHEMBL3633943)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration against retinoic acid receptor gamma in COS-7 cells co-expressing DR5-tk-CAT reporter; value range (0.1-0.5)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P80PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132507(CHEMBL3633943)copy SMILEScopy InChI
Affinity DataEC50:  60nMAssay Description:Effective concentration against retinoic acid receptor gamma in COS-7 cells co-expressing DR5-tk-CAT reporter; value range (0.6-1.5)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P80PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132507(CHEMBL3633943)copy SMILEScopy InChI
Affinity DataEC50:  360nMAssay Description:In vitro binding affinity for PPAR-alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P80PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132507(CHEMBL3633943)copy SMILEScopy InChI
Affinity DataEC50:  360nMAssay Description:Effective concentration against retinoic acid receptor alpha in COS-7 cells co-expressing DR5-tk-CAT reporter; value range (5.6-59.1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P80PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132507(CHEMBL3633943)copy SMILEScopy InChI
Affinity DataEC50:  363nMAssay Description:Effective concentration against retinoic acid receptor beta in COS-7 cells co-expressing DR5-tk-CAT reporter; value range (6.1-9.8)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P80PubMed