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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Amgen Inc.
Curated by
ChEMBL
Ligand
BDBM50138299
((S)-4-(4-Acetyl-piperazin-1-yl)-2-(4-chloro-benzyl...)
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Affinity Data
IC50: 11nM
Assay Description:
Inhibitory activity against [125I]-NDP-alpha-MSH binding to the human melanocortin 4 receptor
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2902363
PubMed
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Amgen Inc.
Curated by
ChEMBL
Ligand
BDBM50138299
((S)-4-(4-Acetyl-piperazin-1-yl)-2-(4-chloro-benzyl...)
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copy InChI
Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibitory activity against human melanocortin 3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2902363
PubMed
Target
Melanocyte-stimulating hormone receptor
(Mus musculus)
Amgen Inc.
Curated by
ChEMBL
Ligand
BDBM50138299
((S)-4-(4-Acetyl-piperazin-1-yl)-2-(4-chloro-benzyl...)
copy SMILES
copy InChI
Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibitory activity against mouse melanocortin 1 receptor
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2902363
PubMed
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Amgen Inc.
Curated by
ChEMBL
Ligand
BDBM50138299
((S)-4-(4-Acetyl-piperazin-1-yl)-2-(4-chloro-benzyl...)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Intracellular level of cAMP in cells expressing the melanocortin 4 receptor
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2902363
PubMed