Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMelanocortin receptor 4(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM160196(US9040663, 42)copy SMILES
Affinity DataKi:  6nM ΔG°:  -48.8kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29885SKUS Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM160196(US9040663, 42)copy SMILES
Affinity DataKi:  420nM ΔG°:  -37.9kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29885SKUS Patent