Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250590(CHEMBL4081900)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TJBPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250590(CHEMBL4081900)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TJBPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250590(CHEMBL4081900)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TJBPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250590(CHEMBL4081900)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TJBPubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250590(CHEMBL4081900)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation measured after 3 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TJBPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250590(CHEMBL4081900)copy SMILEScopy InChI
Affinity DataEC50:  200nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9TJBPubMed