Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetMitogen-activated protein kinase 6(Homo sapiens (Human))TBA
LigandPNGBDBM365141(9-isopropyl-6-methyl-4-(2- ((1-methyl-1H-pyrazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 0.512nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KP85BCUS Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
GENENTECH, INC.

US Patent
LigandPNGBDBM365141(9-isopropyl-6-methyl-4-(2- ((1-methyl-1H-pyrazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 0.512nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ144NUS Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
GENENTECH, INC.

US Patent
LigandPNGBDBM365140(9-isopropyl-6-methyl-4-(2- ((1-methyl-1H-pyrazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 0.512nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9MJ5US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
GENENTECH, INC.

US Patent
LigandPNGBDBM365140(9-isopropyl-6-methyl-4-(2- ((1-methyl-1H-pyrazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 0.512nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X88ZRUS Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
GENENTECH, INC.

US Patent
LigandPNGBDBM365141(9-isopropyl-6-methyl-4-(2- ((1-methyl-1H-pyrazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 0.512nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9MPZUS Patent
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))TBA
LigandPNGBDBM365140(9-isopropyl-6-methyl-4-(2- ((1-methyl-1H-pyrazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 369nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KP85BCUS Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
GENENTECH, INC.

US Patent
LigandPNGBDBM383320(9-isopropyl-6-methyl-4-(2- ((1-methyl-1H-pyrazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 369nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X88ZRUS Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
GENENTECH, INC.

US Patent
LigandPNGBDBM365141(9-isopropyl-6-methyl-4-(2- ((1-methyl-1H-pyrazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 369nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9MJ5US Patent