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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Carboxypeptidase B2
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50135934
(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)
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Affinity Data
IC50: 2.70nM
Assay Description:
In vitro inhibition of purified Carboxypeptidase B (CPB) by clot lysis assay in human plasma
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q27H1J0Z
PubMed
Target
Carboxypeptidase B
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50135934
(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)
copy SMILES
copy InChI
Affinity Data
IC50: 4nM
Assay Description:
Inhibition of human carboxypeptidase B (CPB)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2N8797S
PubMed
Target
Carboxypeptidase B2
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50135934
(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)
copy SMILES
copy InChI
Affinity Data
IC50: 5nM
Assay Description:
Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2N8797S
PubMed
Target
Carboxypeptidase A1
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50135934
(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)
copy SMILES
copy InChI
Affinity Data
IC50: 1.40E+3nM
Assay Description:
In vitro inhibition of Carboxypeptidase A (CPA) was determined by clot lysis assay using human plasma
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q27H1J0Z
PubMed
Target
Carboxypeptidase A1
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50135934
(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)
copy SMILES
copy InChI
Affinity Data
IC50: 1.40E+3nM
Assay Description:
In vitro inhibition of Carboxypeptidase A (CPA) was determined by clot lysis assay using human plasma
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q27H1J0Z
PubMed
Target
Carboxypeptidase M
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50135934
(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)
copy SMILES
copy InChI
Affinity Data
IC50: 5.00E+4nM
Assay Description:
In vitro inhibition of purified Carboxypeptidase M (CPM) by clot lysis assay in human plasma
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q27H1J0Z
PubMed
Target
Carboxypeptidase M
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50135934
(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)
copy SMILES
copy InChI
Affinity Data
IC50: 5.00E+4nM
Assay Description:
In vitro inhibition of purified Carboxypeptidase M (CPM) by clot lysis assay in human plasma
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q27H1J0Z
PubMed