Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataKi:  2.51nMAssay Description:Displacement of [3H]PGE2 from EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataKi:  316nMAssay Description:Binding affinity to TP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Activity at EP3 receptor by FLIPR methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:Binding affinity to rat EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2P68PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Binding affinity to human EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 1.58E+3nMAssay Description:Activity at TP receptor by FLIPR methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Activity at PGF2alpha receptor by FLIPR methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50259548(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG receptor by FLIPR methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879N5PubMed