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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50323151
(CHEMBL1209252 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
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Affinity Data
IC50: 29nM
Assay Description:
Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2C829GJ
PubMed
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50323151
(CHEMBL1209252 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
copy SMILES
copy InChI
Affinity Data
IC50: 29nM
Assay Description:
Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2C829GJ
PubMed
Target
Melanocortin receptor 5
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50323151
(CHEMBL1209252 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
copy SMILES
copy InChI
Affinity Data
IC50: 660nM
Assay Description:
Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2C829GJ
PubMed
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50323151
(CHEMBL1209252 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
copy SMILES
copy InChI
Affinity Data
IC50: 1.80E+3nM
Assay Description:
Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2C829GJ
PubMed
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50323151
(CHEMBL1209252 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
copy SMILES
copy InChI
Affinity Data
IC50: 6.50E+3nM
Assay Description:
Displacement of [125I]NDP-alpha-MSH from human MC3 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2C829GJ
PubMed
Target
Melanocortin receptor 5
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50323151
(CHEMBL1209252 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
copy SMILES
copy InChI
Affinity Data
EC50: 2.80E+3nM
Assay Description:
Agonist activity at human MC5 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2C829GJ
PubMed
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50323151
(CHEMBL1209252 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
copy SMILES
copy InChI
Affinity Data
EC50: 25nM
Assay Description:
Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2C829GJ
PubMed
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50323151
(CHEMBL1209252 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
copy SMILES
copy InChI
Affinity Data
EC50: 890nM
Assay Description:
Agonist activity at human MC1 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2C829GJ
PubMed
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50323151
(CHEMBL1209252 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
copy SMILES
copy InChI
Affinity Data
EC50: 2.00E+3nM
Assay Description:
Agonist activity at human MC3 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2C829GJ
PubMed