Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50263821(CHEMBL4080223)copy SMILEScopy InChI
Affinity DataKi:  4.68E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R LBD expressed in HEK293 cell membranes incubated for 16 to 23 hrs in dark by scintillation proxi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736TCZPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50263821(CHEMBL4080223)copy SMILEScopy InChI
Affinity DataKi:  6.31E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R LBD expressed in HEK293 cell membranes incubated for 16 to 23 hrs in dark by scintillation proxi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736TCZPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50263821(CHEMBL4080223)copy SMILEScopy InChI
Affinity DataKi:  3.89E+4nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R LBD expressed in HEK293 cell membranes incubated for 16 to 23 hrs in dark by scintillation proxi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736TCZPubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50263821(CHEMBL4080223)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+4nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC5R LBD expressed in HEK293 cell membranes incubated for 16 to 23 hrs in dark by scintillation proxi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736TCZPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50263821(CHEMBL4080223)copy SMILEScopy InChI
Affinity DataEC50:  1.05E+3nMAssay Description:Agonist activity at human MC4R expressed in high doxycyclin-treated HEK293 cell membranes assessed as increase in cAMP production after 15 mins by HT...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736TCZPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50263821(CHEMBL4080223)copy SMILEScopy InChI
Affinity DataEC50:  1.07E+4nMAssay Description:Agonist activity at human MC4R expressed in low doxycyclin-treated HEK293 cell membranes assessed as increase in cAMP production after 45 mins by HTR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736TCZPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50263821(CHEMBL4080223)copy SMILEScopy InChI
Affinity DataEC50:  7.41E+3nMAssay Description:Agonist activity at human MC3R expressed in low doxycyclin-treated HEK293 cell membranes assessed as increase in cAMP production after 45 mins by HTR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736TCZPubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50263821(CHEMBL4080223)copy SMILEScopy InChI
Affinity DataEC50:  1.32E+3nMAssay Description:Agonist activity at human MC1R expressed in low doxycyclin-treated HEK293 cell membranes assessed as increase in cAMP production after 45 mins by HTR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736TCZPubMed