Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340463(CHEMBL1761871 | cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3S0GPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340463(CHEMBL1761871 | cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3S0GPubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340463(CHEMBL1761871 | cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Agonist activity at human MC5 receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3S0GPubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340463(CHEMBL1761871 | cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3S0GPubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340463(CHEMBL1761871 | cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)copy SMILEScopy InChI
Affinity DataEC50:  420nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3S0GPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50340463(CHEMBL1761871 | cis-(3S,5R)-N-((R)-1-(4-(tert-buty...)copy SMILEScopy InChI
Affinity DataEC50:  13nMAssay Description:Agonist activity at human MC4 receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3S0GPubMed