Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetProstaglandin D2 receptor(Homo sapiens (Human))
Shionogi & Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50060452((Z)-7-{(1R,2R,3S,5S)-2-[(Benzo[b]thiophene-3-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of cAMP formation evoked by the prostaglandin D2 receptor in human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959GP9PubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Shionogi & Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50060452((Z)-7-{(1R,2R,3S,5S)-2-[(Benzo[b]thiophene-3-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of [3H]-PGD-2 specific binding to Prostaglandin D2 receptor fromhuman platelet membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959GP9PubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Shionogi & Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50060452((Z)-7-{(1R,2R,3S,5S)-2-[(Benzo[b]thiophene-3-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of [3H]- (+)-S-145 specific binding to human platelet membranes in TXA2 receptor (TP) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959GP9PubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Shionogi & Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50060452((Z)-7-{(1R,2R,3S,5S)-2-[(Benzo[b]thiophene-3-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cAMP formation by carbacyclin in Prostaglandin I2 receptor (IP) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959GP9PubMed