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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Integrin alpha-5
(Homo sapiens (Human))
Shire Orphan Therapies GmbH
US Patent
Ligand
BDBM141978
(US8927534, 29)
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copy InChI
Affinity Data
IC50: 100nM
pH: 9.6 T: 2°C
Assay Description:
Fibronectin was diluted with coating buffer (15 mM Na2CO3, 35 mM NaHCO3, pH 9.6) and coated with 100 uL/well to Nunc-Immuno maxisorp plates (Nalge Nu...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2TQ607Q
US Patent
Target
Integrin alpha-IIb
(Homo sapiens (Human))
Shire Orphan Therapies GmbH
US Patent
Ligand
BDBM141978
(US8927534, 29)
copy SMILES
copy InChI
Affinity Data
IC50: 1.00E+3nM
pH: 9.6 T: 2°C
Assay Description:
Fibrinogen was diluted with coating buffer (15 mM Na2CO3, 35 mM NaHCO3, pH 9.6) and coated with 100 uL/well to Nunc-Immuno maxisorp plates over night...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2TQ607Q
US Patent