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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
(Homo sapiens (Human))
AstraZeneca
Curated by
ChEMBL
Ligand
BDBM50433271
(CHEMBL2376327)
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Affinity Data
IC50: 63nM
Assay Description:
Inhibition of human recombinant MGAT2 expressed in insect cell membrane using 2-oleoyl-sn-glycerol and oleoyl coenzyme A as substrate after 40 mins b...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2GB25DM
PubMed
Target
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
(Homo sapiens (Human))
AstraZeneca
Curated by
ChEMBL
Ligand
BDBM50433271
(CHEMBL2376327)
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copy InChI
Affinity Data
IC50: 158nM
Assay Description:
Inhibition of human recombinant MGAT1 expressed in insect cell membrane using 2-oleyl-sn-glycerol and [14C]-oleyl-coenzyme A as substrate after 10 to...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2GB25DM
PubMed
Target
Diacylglycerol O-acyltransferase 2
(Homo sapiens (Human))
AstraZeneca
Curated by
ChEMBL
Ligand
BDBM50433271
(CHEMBL2376327)
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Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibition of human recombinant DGAT2 using dioleoyl-sn-glycerol and [14C]oleoyl coenzyme A as substrate after 30 mins by liquid scintillation counti...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2GB25DM
PubMed
Target
Diacylglycerol O-acyltransferase 1
(Homo sapiens (Human))
AstraZeneca
Curated by
ChEMBL
Ligand
BDBM50433271
(CHEMBL2376327)
copy SMILES
copy InChI
Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibition of human recombinant DGAT1 expressed in Sf9 cells using dioleoyl-sn-glycerol and [14C]oleoyl coenzyme A as substrate after 30 mins by liqu...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2GB25DM
PubMed
Target
Acyl-CoA wax alcohol acyltransferase 1
(Homo sapiens (Human))
AstraZeneca
Curated by
ChEMBL
Ligand
BDBM50433271
(CHEMBL2376327)
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copy InChI
Affinity Data
IC50: 1.00E+5nM
Assay Description:
Inhibition of human recombinant AWAT1 expressed in insect cell membrane using palmitoleyl alcohol and [14C]stearoyl coenzyme A as substrate after 10 ...
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2GB25DM
PubMed
Target
Acyl-CoA wax alcohol acyltransferase 2
(Homo sapiens (Human))
AstraZeneca
Curated by
ChEMBL
Ligand
BDBM50433271
(CHEMBL2376327)
copy SMILES
copy InChI
Affinity Data
IC50: 1.00E+5nM
Assay Description:
Inhibition of human recombinant AWAT2 expressed in insect cell membrane using cetyl alcohol and [14C]oleoyl coenzyme A as substrate after 10 to 15 mi...
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2GB25DM
PubMed