Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211377(Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip-Pro8-Trp9-Lys10...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ10QMPubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211377(Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip-Pro8-Trp9-Lys10...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ10QMPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211377(Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip-Pro8-Trp9-Lys10...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ10QMPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211377(Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip-Pro8-Trp9-Lys10...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of [125I]NDPalphaMSH from human cloned MC3R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ10QMPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211377(Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip-Pro8-Trp9-Lys10...)copy SMILEScopy InChI
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at human MC3R expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ10QMPubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211377(Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip-Pro8-Trp9-Lys10...)copy SMILEScopy InChI
Affinity DataEC50:  5.30nMAssay Description:Agonist activity at human melanocortin receptor 1b expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ10QMPubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211377(Ac-Nle4-cyclo(Asp5-His6-D-4,4'-Bip-Pro8-Trp9-Lys10...)copy SMILEScopy InChI
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at human MC5R expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ10QMPubMed