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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Melanocortin receptor 5
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50211389
(Ac-Nle4-cyclo(Asp5-His6-D-Tyr(Et)-Pro8-Trp9-Lys10)...)
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Affinity Data
IC50: 340nM
Assay Description:
Displacement of [125I]NDPalphaMSH from human cloned MC5R expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2JQ10QM
PubMed
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50211389
(Ac-Nle4-cyclo(Asp5-His6-D-Tyr(Et)-Pro8-Trp9-Lys10)...)
copy SMILES
copy InChI
Affinity Data
IC50: 430nM
Assay Description:
Displacement of [125I]NDPalphaMSH from human cloned melanocortin receptor 1b expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2JQ10QM
PubMed
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50211389
(Ac-Nle4-cyclo(Asp5-His6-D-Tyr(Et)-Pro8-Trp9-Lys10)...)
copy SMILES
copy InChI
Affinity Data
IC50: 1.00E+4nM
Assay Description:
Displacement of [125I]NDPalphaMSH from human cloned MC3R expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2JQ10QM
PubMed
Target
Melanocortin receptor 5
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50211389
(Ac-Nle4-cyclo(Asp5-His6-D-Tyr(Et)-Pro8-Trp9-Lys10)...)
copy SMILES
copy InChI
Affinity Data
EC50: 270nM
Assay Description:
Agonist activity at human MC5R expressed in CHO cells assessed as cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2JQ10QM
PubMed
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50211389
(Ac-Nle4-cyclo(Asp5-His6-D-Tyr(Et)-Pro8-Trp9-Lys10)...)
copy SMILES
copy InChI
Affinity Data
EC50: 60nM
Assay Description:
Agonist activity at human melanocortin receptor 1b expressed in CHO cells assessed as cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2JQ10QM
PubMed
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50211389
(Ac-Nle4-cyclo(Asp5-His6-D-Tyr(Et)-Pro8-Trp9-Lys10)...)
copy SMILES
copy InChI
Affinity Data
EC50: >2.50E+3nM
Assay Description:
Agonist activity at human MC3R expressed in CHO cells assessed as cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2JQ10QM
PubMed