Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies, Inc.

US Patent
LigandPNGBDBM250691(US9447148, 9.60)copy SMILEScopy InChI
Affinity DataKi:  18nM ΔG°:  -46.0kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HD2US Patent
TargetMelanocortin receptor 4(Homo sapiens (Human))
Palatin Technologies, Inc.

US Patent
LigandPNGBDBM250691(US9447148, 9.60)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nM ΔG°:  -29.7kJ/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HD2US Patent
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Palatin Technologies, Inc.

US Patent
LigandPNGBDBM250691(US9447148, 9.60)copy SMILEScopy InChI
Affinity DataEC50:  0.800nMpH: 7.5 T: 2°CAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HD2US Patent