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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Nitric oxide synthase, inducible
(Homo sapiens (Human))
Pfizer Inc.
Curated by
ChEMBL
Ligand
BDBM50066785
(4-Methyl-5-propyl-pyrrolidin-(2E)-ylideneamine; hy...)
copy SMILES
copy InChI
Affinity Data
IC50: 300nM
Assay Description:
Inhibition of cloned (from RNA) human inducible nitric oxide synthase (hiNOS)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2XP75MP
PubMed
Target
Nitric oxide synthase, brain
(Homo sapiens (Human))
Pfizer Inc.
Curated by
ChEMBL
Ligand
BDBM50066785
(4-Methyl-5-propyl-pyrrolidin-(2E)-ylideneamine; hy...)
copy SMILES
copy InChI
Affinity Data
IC50: 390nM
Assay Description:
Inhibition of cloned (from RNA) human Neuronal nitric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2XP75MP
PubMed
Target
Nitric oxide synthase, inducible
(Homo sapiens (Human))
Pfizer Inc.
Curated by
ChEMBL
Ligand
BDBM50066785
(4-Methyl-5-propyl-pyrrolidin-(2E)-ylideneamine; hy...)
copy SMILES
copy InChI
Affinity Data
IC50: 2.00E+3nM
Assay Description:
Inhibitory activity against Inducible nitric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q218377V
PubMed
Target
Nitric oxide synthase, endothelial
(Homo sapiens (Human))
Pfizer Inc.
Curated by
ChEMBL
Ligand
BDBM50066785
(4-Methyl-5-propyl-pyrrolidin-(2E)-ylideneamine; hy...)
copy SMILES
copy InChI
Affinity Data
IC50: 3.50E+3nM
Assay Description:
Inhibition of cloned (from RNA) human endothelial constitutive Endothelial nitric oxide synthase (heNOS)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2XP75MP
PubMed
Target
Nitric oxide synthase, brain
(Homo sapiens (Human))
Pfizer Inc.
Curated by
ChEMBL
Ligand
BDBM50066785
(4-Methyl-5-propyl-pyrrolidin-(2E)-ylideneamine; hy...)
copy SMILES
copy InChI
Affinity Data
IC50: 4.80E+3nM
Assay Description:
Inhibitory activity against Neuronal nitric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q218377V
PubMed
Target
Nitric oxide synthase, endothelial
(Homo sapiens (Human))
Pfizer Inc.
Curated by
ChEMBL
Ligand
BDBM50066785
(4-Methyl-5-propyl-pyrrolidin-(2E)-ylideneamine; hy...)
copy SMILES
copy InChI
Affinity Data
IC50: 4.90E+4nM
Assay Description:
Inhibitory activity against Endothelial nitric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q218377V
PubMed