Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
NeurAxon Inc.

Curated by ChEMBL
LigandPNGBDBM106740(CHEMBL1823369 | US8586620, 158)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human nNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine into [3H]-L-citrull...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4X63PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
NeurAxon Inc.

Curated by ChEMBL
LigandPNGBDBM106740(CHEMBL1823369 | US8586620, 158)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348J0KUS Patent
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
NeurAxon Inc.

Curated by ChEMBL
LigandPNGBDBM106740(CHEMBL1823369 | US8586620, 158)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of recombinant human eNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine into [3H]-L-citrull...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4X63PubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
NeurAxon Inc.

Curated by ChEMBL
LigandPNGBDBM106740(CHEMBL1823369 | US8586620, 158)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+4nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348J0KUS Patent