Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179138(CHEMBL380727 | ethyl (1-((R)-3-(4-chlorophenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4Q5SPubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179138(CHEMBL380727 | ethyl (1-((R)-3-(4-chlorophenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4Q5SPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179138(CHEMBL380727 | ethyl (1-((R)-3-(4-chlorophenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4Q5SPubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179138(CHEMBL380727 | ethyl (1-((R)-3-(4-chlorophenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1BR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4Q5SPubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179138(CHEMBL380727 | ethyl (1-((R)-3-(4-chlorophenyl)-2-...)copy SMILEScopy InChI
Affinity DataEC50:  550nMAssay Description:Activity against human MC3R by cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4Q5SPubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179138(CHEMBL380727 | ethyl (1-((R)-3-(4-chlorophenyl)-2-...)copy SMILEScopy InChI
Affinity DataEC50:  970nMAssay Description:Activity against human MC1BR by cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4Q5SPubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179138(CHEMBL380727 | ethyl (1-((R)-3-(4-chlorophenyl)-2-...)copy SMILEScopy InChI
Affinity DataEC50:  14nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4Q5SPubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179138(CHEMBL380727 | ethyl (1-((R)-3-(4-chlorophenyl)-2-...)copy SMILEScopy InChI
Affinity DataEC50:  3.60E+3nMAssay Description:Activity against human MC5R by cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4Q5SPubMed