Home
About
Info
Download
WebServices
Contact
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50179138
(CHEMBL380727 | ethyl (1-((R)-3-(4-chlorophenyl)-2-...)
copy SMILES
copy InChI
Affinity Data
IC50: 8.10nM
Assay Description:
Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2NG4Q5S
PubMed
Target
Melanocortin receptor 5
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50179138
(CHEMBL380727 | ethyl (1-((R)-3-(4-chlorophenyl)-2-...)
copy SMILES
copy InChI
Affinity Data
IC50: 630nM
Assay Description:
Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2NG4Q5S
PubMed
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50179138
(CHEMBL380727 | ethyl (1-((R)-3-(4-chlorophenyl)-2-...)
copy SMILES
copy InChI
Affinity Data
IC50: 630nM
Assay Description:
Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2NG4Q5S
PubMed
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50179138
(CHEMBL380727 | ethyl (1-((R)-3-(4-chlorophenyl)-2-...)
copy SMILES
copy InChI
Affinity Data
IC50: 1.10E+3nM
Assay Description:
Displacement of [125I]NDP-alpha-MSH from human MC1BR expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2NG4Q5S
PubMed
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50179138
(CHEMBL380727 | ethyl (1-((R)-3-(4-chlorophenyl)-2-...)
copy SMILES
copy InChI
Affinity Data
EC50: 550nM
Assay Description:
Activity against human MC3R by cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2NG4Q5S
PubMed
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50179138
(CHEMBL380727 | ethyl (1-((R)-3-(4-chlorophenyl)-2-...)
copy SMILES
copy InChI
Affinity Data
EC50: 970nM
Assay Description:
Activity against human MC1BR by cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2NG4Q5S
PubMed
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50179138
(CHEMBL380727 | ethyl (1-((R)-3-(4-chlorophenyl)-2-...)
copy SMILES
copy InChI
Affinity Data
EC50: 14nM
Assay Description:
Activity against human MC4R by cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2NG4Q5S
PubMed
Target
Melanocortin receptor 5
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50179138
(CHEMBL380727 | ethyl (1-((R)-3-(4-chlorophenyl)-2-...)
copy SMILES
copy InChI
Affinity Data
EC50: 3.60E+3nM
Assay Description:
Activity against human MC5R by cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2NG4Q5S
PubMed