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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Nitric oxide synthase, inducible
(Homo sapiens (Human))
AstraZeneca R& D Charnwood
Curated by
ChEMBL
Ligand
BDBM50124528
(CHEMBL170176 | ethyl 4'-amino-1H,1'H-spiro[piperid...)
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copy InChI
Affinity Data
IC50: 300nM
Assay Description:
Inhibitory activity of compound against human inducible nitiric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2S75H3M
PubMed
Target
Nitric oxide synthase, inducible
(Homo sapiens (Human))
AstraZeneca R& D Charnwood
Curated by
ChEMBL
Ligand
BDBM50124528
(CHEMBL170176 | ethyl 4'-amino-1H,1'H-spiro[piperid...)
copy SMILES
copy InChI
Affinity Data
IC50: 300nM
Assay Description:
Inhibition of iNOS
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2GX4CF5
PubMed
Target
Nitric oxide synthase, brain
(Homo sapiens (Human))
AstraZeneca R& D Charnwood
Curated by
ChEMBL
Ligand
BDBM50124528
(CHEMBL170176 | ethyl 4'-amino-1H,1'H-spiro[piperid...)
copy SMILES
copy InChI
Affinity Data
IC50: 5.00E+4nM
Assay Description:
Inhibitory activity against human neuronal nitiric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2S75H3M
PubMed
Target
Nitric oxide synthase, endothelial
(Homo sapiens (Human))
AstraZeneca R& D Charnwood
Curated by
ChEMBL
Ligand
BDBM50124528
(CHEMBL170176 | ethyl 4'-amino-1H,1'H-spiro[piperid...)
copy SMILES
copy InChI
Affinity Data
IC50: 1.00E+5nM
Assay Description:
Inhibitory activity against human endothelial nitiric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2S75H3M
PubMed