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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Mu-type opioid receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50386384
(CHEMBL2046874)
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Affinity Data
Ki: 170nM
Assay Description:
Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK-293 cells by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2TX3GF4
PubMed
Target
Nitric oxide synthase, brain
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50386384
(CHEMBL2046874)
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copy InChI
Affinity Data
IC50: 1.77E+3nM
Assay Description:
Inhibition of human recombinant nNOS assessed as conversion of [3H]L-arginine to [3H]L-citrulline preincubated for 15 mins measured after 45 mins by ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2TX3GF4
PubMed
Target
Nitric oxide synthase, endothelial
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50386384
(CHEMBL2046874)
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copy InChI
Affinity Data
IC50: 4.04E+3nM
Assay Description:
Inhibition of human recombinant eNOS assessed as conversion of [3H]L-arginine to [3H]L-citrulline preincubated for 15 mins measured after 45 mins by ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2TX3GF4
PubMed
Target
Mu-type opioid receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50386384
(CHEMBL2046874)
copy SMILES
copy InChI
Affinity Data
EC50: 2.20E+3nM
Assay Description:
Agonist activity at human mu opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 1 hr by HTRF ...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2TX3GF4
PubMed