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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50417192
(CHEMBL1271476)
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Affinity Data
Ki: 50.1nM
Assay Description:
Antagonist activity at human EP3 receptor expressed in human U2OS cells assessed as inhibition of PGE2-induced intracellular calcium mobilization by ...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
BindingDB Entry DOI:
10.7270/Q25M65Z8
PubMed
Target
Prostaglandin E2 receptor EP3 subtype
(RAT)
GlaxoSmithKline Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50417192
(CHEMBL1271476)
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Affinity Data
Ki: 158nM
Assay Description:
Inhibition of rat EP3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
BindingDB Entry DOI:
10.7270/Q25M65Z8
PubMed
Target
Cytochrome P450 1A2
(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50417192
(CHEMBL1271476)
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Affinity Data
Ki: 2.00E+3nM
Assay Description:
Inhibition of CYP1A2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q25M65Z8
PubMed
Target
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50417192
(CHEMBL1271476)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Displacement of radioligand from human EP1 receptor
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q25M65Z8
PubMed
Target
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50417192
(CHEMBL1271476)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Displacement of radioligand from human EP4 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q25M65Z8
PubMed
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50417192
(CHEMBL1271476)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Displacement of radioligand from human TP receptor
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q25M65Z8
PubMed
Target
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50417192
(CHEMBL1271476)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Displacement of radioligand from human EP2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q25M65Z8
PubMed
Target
Prostaglandin F2-alpha receptor
(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50417192
(CHEMBL1271476)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Displacement of radioligand from human FP receptor
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
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CHEMBL
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PC sid
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In Depth
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Article
BindingDB Entry DOI:
10.7270/Q25M65Z8
PubMed
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50417192
(CHEMBL1271476)
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Affinity Data
Ki: >1.00E+4nM
Assay Description:
Displacement of [3H]dofetilide from human ERG
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q25M65Z8
PubMed