Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 17 hits in this display   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen Ltd.

Curated by ChEMBL
LigandPNGBDBM50161745(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Inhibition of CRTH2More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen Ltd.

Curated by ChEMBL
LigandPNGBDBM50161745(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Inhibition of [3H]PGD-2 binding to human chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen Ltd.

Curated by ChEMBL
LigandPNGBDBM50161745(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Binding affinity to human recombinant CRTH2 receptor by cell based radioligand equilibrium competition assayMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen Ltd.

Curated by ChEMBL
LigandPNGBDBM50161745(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Binding affinity to human recombinant CRTH2 receptor by cell based radioligand equilibrium competition assayMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50161745(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataKi:  653nMAssay Description:Binding affinity to prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HTHPubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50161745(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataKi:  1.12E+3nMAssay Description:Binding affinity to prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HTHPubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50161745(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of [3H]-PGD-2 binding to human Prostaglandin D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0DMDPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50161745(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataKi:  1.39E+3nMAssay Description:Binding affinity to thromboxane receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HTHPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50161745(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataKi:  6.85E+3nMAssay Description:Binding affinity to thromboxane receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959HTHPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50161745(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]-SQ-29,548 binding to human Thromboxane A2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0DMDPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50161745(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of TP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z0398RPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen Ltd.

Curated by ChEMBL
LigandPNGBDBM50161745(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of beta-arrestin translocation at human chemoattractant receptor-homologous molecule expressed on TH2 cells in BRET assayMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen Ltd.

Curated by ChEMBL
LigandPNGBDBM50161745(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of beta-arrestin translocation at human chemoattractant receptor-homologous molecule expressed on TH2 cells in BRET assayMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen Ltd.

Curated by ChEMBL
LigandPNGBDBM50161745(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of CRTH2More data for this Ligand-Target Pair
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50161745(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of beta-arrestin translocation at human Thromboxane A2 receptor in BRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0DMDPubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50161745(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PGD2-induced inositol phosphate formation at human Prostaglandin D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0DMDPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50161745(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of beta-arrestin translocation at Thromboxane A2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0DMDPubMed