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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
17
hits in this display
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Oxagen Ltd.
Curated by
ChEMBL
Ligand
BDBM50161745
(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)
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Affinity Data
Ki: 0.600nM
Assay Description:
Inhibition of CRTH2
More data for this Ligand-Target Pair
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Article
BindingDB Entry DOI:
10.7270/Q2Z0398R
PubMed
PDB
3D Structure (crystal)
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Oxagen Ltd.
Curated by
ChEMBL
Ligand
BDBM50161745
(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)
copy SMILES
copy InChI
Affinity Data
Ki: 0.600nM
Assay Description:
Inhibition of [3H]PGD-2 binding to human chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)
More data for this Ligand-Target Pair
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Article
BindingDB Entry DOI:
10.7270/Q24J0DMD
PubMed
PDB
3D Structure (crystal)
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Oxagen Ltd.
Curated by
ChEMBL
Ligand
BDBM50161745
(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)
copy SMILES
copy InChI
Affinity Data
Ki: 1.5nM
Assay Description:
Binding affinity to human recombinant CRTH2 receptor by cell based radioligand equilibrium competition assay
More data for this Ligand-Target Pair
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Article
BindingDB Entry DOI:
10.7270/Q2959HTH
PubMed
PDB
3D Structure (crystal)
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Oxagen Ltd.
Curated by
ChEMBL
Ligand
BDBM50161745
(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)
copy SMILES
copy InChI
Affinity Data
Ki: 6nM
Assay Description:
Binding affinity to human recombinant CRTH2 receptor by cell based radioligand equilibrium competition assay
More data for this Ligand-Target Pair
Target Info
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In Depth
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Article
BindingDB Entry DOI:
10.7270/Q2959HTH
PubMed
PDB
3D Structure (crystal)
Target
Prostaglandin D2 receptor
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50161745
(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)
copy SMILES
copy InChI
Affinity Data
Ki: 653nM
Assay Description:
Binding affinity to prostanoid DP1 receptor
More data for this Ligand-Target Pair
Target Info
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CHEMBL
MCE
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In Depth
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Article
BindingDB Entry DOI:
10.7270/Q2959HTH
PubMed
Target
Prostaglandin D2 receptor
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50161745
(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)
copy SMILES
copy InChI
Affinity Data
Ki: 1.12E+3nM
Assay Description:
Binding affinity to prostanoid DP1 receptor
More data for this Ligand-Target Pair
Target Info
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CHEMBL
MCE
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PC sid
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In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2959HTH
PubMed
Target
Prostaglandin D2 receptor
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50161745
(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)
copy SMILES
copy InChI
Affinity Data
Ki: 1.20E+3nM
Assay Description:
Inhibition of [3H]-PGD-2 binding to human Prostaglandin D2 receptor
More data for this Ligand-Target Pair
Target Info
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Article
BindingDB Entry DOI:
10.7270/Q24J0DMD
PubMed
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50161745
(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)
copy SMILES
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Affinity Data
Ki: 1.39E+3nM
Assay Description:
Binding affinity to thromboxane receptor
More data for this Ligand-Target Pair
Target Info
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CHEMBL
MCE
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In Depth
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Article
BindingDB Entry DOI:
10.7270/Q2959HTH
PubMed
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50161745
(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)
copy SMILES
copy InChI
Affinity Data
Ki: 6.85E+3nM
Assay Description:
Binding affinity to thromboxane receptor
More data for this Ligand-Target Pair
Target Info
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GoogleScholar
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CHEMBL
MCE
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PC sid
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In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2959HTH
PubMed
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50161745
(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Inhibition of [3H]-SQ-29,548 binding to human Thromboxane A2 receptor
More data for this Ligand-Target Pair
Target Info
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CHEMBL
MCE
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PC sid
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In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q24J0DMD
PubMed
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50161745
(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Inhibition of TP receptor
More data for this Ligand-Target Pair
Target Info
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GoogleScholar
Ligand Info
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CHEMBL
MCE
PC cid
PC sid
PDB
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In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2Z0398R
PubMed
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Oxagen Ltd.
Curated by
ChEMBL
Ligand
BDBM50161745
(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)
copy SMILES
copy InChI
Affinity Data
IC50: 1.20nM
Assay Description:
Inhibition of beta-arrestin translocation at human chemoattractant receptor-homologous molecule expressed on TH2 cells in BRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q24J0DMD
PubMed
PDB
3D Structure (crystal)
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Oxagen Ltd.
Curated by
ChEMBL
Ligand
BDBM50161745
(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)
copy SMILES
copy InChI
Affinity Data
IC50: 3nM
Assay Description:
Inhibition of beta-arrestin translocation at human chemoattractant receptor-homologous molecule expressed on TH2 cells in BRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q24J0DMD
PubMed
PDB
3D Structure (crystal)
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Oxagen Ltd.
Curated by
ChEMBL
Ligand
BDBM50161745
(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)
copy SMILES
copy InChI
Affinity Data
IC50: 3.60nM
Assay Description:
Inhibition of CRTH2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2Z0398R
PubMed
PDB
3D Structure (crystal)
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50161745
(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)
copy SMILES
copy InChI
Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibition of beta-arrestin translocation at human Thromboxane A2 receptor in BRET assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q24J0DMD
PubMed
Target
Prostaglandin D2 receptor
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50161745
(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)
copy SMILES
copy InChI
Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibition of PGD2-induced inositol phosphate formation at human Prostaglandin D2 receptor
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q24J0DMD
PubMed
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50161745
(CHEMBL179036 | {3-[((R)-4-Fluoro-benzenesulfonyl)-...)
copy SMILES
copy InChI
Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibition of beta-arrestin translocation at Thromboxane A2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q24J0DMD
PubMed