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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
7TM Pharma A/S
Curated by
ChEMBL
Ligand
BDBM50161747
(3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...)
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Affinity Data
Ki: 1.90nM
Assay Description:
Inhibition of [3H]PGD-2 binding to human chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q24J0DMD
PubMed
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
7TM Pharma A/S
Curated by
ChEMBL
Ligand
BDBM50161747
(3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...)
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copy InChI
Affinity Data
Ki: 3.00E+3nM
Assay Description:
Inhibition of [3H]-SQ-29,548 binding to human Thromboxane A2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q24J0DMD
PubMed
Target
Prostaglandin D2 receptor
(Homo sapiens (Human))
7TM Pharma A/S
Curated by
ChEMBL
Ligand
BDBM50161747
(3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...)
copy SMILES
copy InChI
Affinity Data
Ki: 6.10E+3nM
Assay Description:
Inhibition of [3H]-PGD-2 binding to human Prostaglandin D2 receptor
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q24J0DMD
PubMed
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
7TM Pharma A/S
Curated by
ChEMBL
Ligand
BDBM50161747
(3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...)
copy SMILES
copy InChI
Affinity Data
IC50: 15nM
Assay Description:
Inhibition of beta-arrestin translocation at human chemoattractant receptor-homologous molecule expressed on TH2 cells in BRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q24J0DMD
PubMed
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
7TM Pharma A/S
Curated by
ChEMBL
Ligand
BDBM50161747
(3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...)
copy SMILES
copy InChI
Affinity Data
IC50: 26nM
Assay Description:
Inhibition of PGD2-induced inositol phosphate formation at human chemoattractant receptor-homologous molecule expressed on TH2 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q24J0DMD
PubMed
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
7TM Pharma A/S
Curated by
ChEMBL
Ligand
BDBM50161747
(3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...)
copy SMILES
copy InChI
Affinity Data
IC50: 4.60E+3nM
Assay Description:
Inhibition of beta-arrestin translocation at human Thromboxane A2 receptor in BRET assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q24J0DMD
PubMed
Target
Prostaglandin D2 receptor
(Homo sapiens (Human))
7TM Pharma A/S
Curated by
ChEMBL
Ligand
BDBM50161747
(3-{(R)-3-[(4-Fluoro-benzenesulfonyl)-methyl-amino]...)
copy SMILES
copy InChI
Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibition of PGD2-induced inositol phosphate formation at human Prostaglandin D2 receptor
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q24J0DMD
PubMed