Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50366915(CHEMBL1788220)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V1a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PMQPubMed
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50366915(CHEMBL1788220)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Evaluated for binding affinity towards vasopressin V2 receptor in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PMQPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50366915(CHEMBL1788220)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Evaluated for intracellular calcium mobilization in HEK- 293 cells transfected to express human vasopressin V1a receptor (Compound 7o)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PMQPubMed
TargetVasopressin V1a receptor(RAT)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50366915(CHEMBL1788220)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Evaluated for binding affinity towards vasopressin V1a receptor in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PMQPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50366915(CHEMBL1788220)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Evaluated for accumulation of cAMP in transfected HEK293 cells expressing human vasopressin V2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PMQPubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50366915(CHEMBL1788220)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Evaluated for intracellular calcium mobilization in HEK293 cells transfected to express human vasopressin V1a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PMQPubMed