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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Nitric oxide synthase, brain
(Homo sapiens (Human))
NeurAxon Inc.
Curated by
ChEMBL
Ligand
BDBM50384900
(CHEMBL2036274)
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copy InChI
Affinity Data
IC50: 300nM
Assay Description:
Inhibition of human nNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2KW5H2V
PubMed
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
NeurAxon Inc.
Curated by
ChEMBL
Ligand
BDBM50384900
(CHEMBL2036274)
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copy InChI
Affinity Data
IC50: 880nM
Assay Description:
Displacement of [3H]nisoxetine from human NET expressed in CHO cells after 120 mins by scintillation counting
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2KW5H2V
PubMed
Target
Nitric oxide synthase, endothelial
(Homo sapiens (Human))
NeurAxon Inc.
Curated by
ChEMBL
Ligand
BDBM50384900
(CHEMBL2036274)
copy SMILES
copy InChI
Affinity Data
IC50: 7.76E+3nM
Assay Description:
Inhibition of human eNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2KW5H2V
PubMed
Target
Nitric oxide synthase, inducible
(Homo sapiens (Human))
NeurAxon Inc.
Curated by
ChEMBL
Ligand
BDBM50384900
(CHEMBL2036274)
copy SMILES
copy InChI
Affinity Data
IC50: 1.45E+4nM
Assay Description:
Inhibition of human iNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2KW5H2V
PubMed