Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
NeurAxon Inc.

Curated by ChEMBL
LigandPNGBDBM50384900(CHEMBL2036274)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of human nNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5H2VPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NeurAxon Inc.

Curated by ChEMBL
LigandPNGBDBM50384900(CHEMBL2036274)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5H2VPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
NeurAxon Inc.

Curated by ChEMBL
LigandPNGBDBM50384900(CHEMBL2036274)copy SMILEScopy InChI
Affinity DataIC50: 7.76E+3nMAssay Description:Inhibition of human eNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5H2VPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
NeurAxon Inc.

Curated by ChEMBL
LigandPNGBDBM50384900(CHEMBL2036274)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of human iNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5H2VPubMed