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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Nitric oxide synthase, brain
(Rattus norvegicus (rat))
Pfizer Global Research and Development
Curated by
ChEMBL
Ligand
BDBM50141078
(6-{4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-naphthal...)
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Affinity Data
IC50: 306nM
Assay Description:
In vitro inhibition of rat neuronal nitric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2J102MT
PubMed
Target
Nitric oxide synthase, brain
(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by
ChEMBL
Ligand
BDBM50141078
(6-{4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-naphthal...)
copy SMILES
copy InChI
Affinity Data
IC50: 390nM
Assay Description:
In vitro inhibition of human neuronal nitric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2J102MT
PubMed
Target
Nitric oxide synthase, inducible
(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by
ChEMBL
Ligand
BDBM50141078
(6-{4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-naphthal...)
copy SMILES
copy InChI
Affinity Data
IC50: 9.38E+3nM
Assay Description:
In vitro inhibition of human inducible nitric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2J102MT
PubMed
Target
Nitric oxide synthase, endothelial
(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by
ChEMBL
Ligand
BDBM50141078
(6-{4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-naphthal...)
copy SMILES
copy InChI
Affinity Data
IC50: 1.20E+4nM
Assay Description:
In vitro inhibition of human endothelial nitric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2J102MT
PubMed